PDB entry 5z0e

View 5z0e on RCSB PDB site
Description: Crystal structure of copper-bound tyrosinase from Streptomyces castaneoglobisporus in complex with the Y98F mutant of the caddie protein obtained by soaking in the hydroxylamine-containing solution for 2 h at 298 K
Class: oxidoreductase/metal binding protein
Keywords: tyrosinase, catalytic mechanism, OXIDOREDUCTASE-METAL BINDING PROTEIN complex
Deposited on 2017-12-19, released 2018-12-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-12-26, with a file datestamp of 2018-12-21.
Experiment type: XRAY
Resolution: 1.16 Å
R-factor: N/A
AEROSPACI score: 0.68 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tyrosinase
    Species: Streptomyces castaneoglobisporus [TaxId:79261]
    Gene: TYRC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q83WS2 (Start-272)
      • conflict (122)
      • expression tag (273)
    Domains in SCOPe 2.08: d5z0ea1, d5z0ea2
  • Chain 'B':
    Compound: MelC
    Species: Streptomyces castaneoglobisporus [TaxId:79261]
    Gene: ORF378
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q83WS1
      • engineered mutation (97)
    Domains in SCOPe 2.08: d5z0eb_
  • Heterogens: CU, PER, NO3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5z0eA (A:)
mtvrknqatltadekrrfvaavlelkrsgrydefvrthnefimsdtdsgertghrspsfl
pwhrrflldfeqalqsvdssvtlpywdwsadrtvraslwapdflggtgrstdgrvmdgpf
aastgnwpinvrvdsrtylrrslggsvaelptraevesvlaisaydlppynsasegfrnh
legwrgvnlhnrvhvwvggqmatgvspndpvfwlhhayvdklwaewqrrhpdsayvptgg
tpdvvdlnetmkpwntvrpadlldhtayytfdalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5z0eA (A:)
tvrknqatltadekrrfvaavlelkrsgrydefvrthnefimsdtdsgertghrspsflp
whrrflldfeqalqsvdssvtlpywdwsadrtvraslwapdflggtgrstdgrvmdgpfa
astgnwpinvrvdsrtylrrslggsvaelptraevesvlaisaydlppynsasegfrnhl
egwrgvnlhnrvhvwvggqmatgvspndpvfwlhhayvdklwaewqrrhpdsayvptggt
pdvvdlnetmkpwntvrpadlldhtayytfdal

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5z0eB (B:)
mpeitrrraltaaaavaatasaavtlaapaasaaghhepaapesfdevykgrriqgrpag
ggahhhehgggyevfvdgvqlhvmrnadgswisvvshfdpvptpraaaraavdelqgapl
lpfpanlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5z0eB (B:)
aapesfdevykgrriqgrpagyevfvdgvqlhvmrnadgswisvvshfdpvptpraaara
avdelqgapllpf