PDB entry 5xyx

View 5xyx on RCSB PDB site
Description: The structure of p38 alpha in complex with a triazol inhibitor
Class: transferase/transferase inhibitor
Keywords: p38 MAP kinase, Transferase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2017-07-11, released 2018-01-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-05-23, with a file datestamp of 2018-05-18.
Experiment type: XRAY
Resolution: 2.61 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5xyxa_
  • Heterogens: FTZ

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5xyxA (A:)
mgsshhhhhhssglvprgshmsqerptfyrqelnktiwevperyqnlspvgsgaygsvca
afdtktglrvavkklsrpfqsiihakrtyrelrllkhmkhenviglldvftparsleefn
dvylvthlmgadlnnivkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavne
dcelkildfglarhtddemtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgr
tlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltqmpkmnfanvfiganpl
avdllekmlvldsdkritaaqalahayfaqyhdpddepvadpydqsfesrdllidewksl
tydevisfvpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >5xyxA (A:)
erptfyrqelnktiwevperyqnlspvsvcaafdtktglrvavkklsrpfqsiihakrty
relrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivltddhvqfliyq
ilrglkyihsadiihrdlkpsnlavnedcelkildfghtddemtgyvatrwyrapeimln
wmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesar
nyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpdd
epvadpydqsfesrdllidewksltydevisfvpppl