PDB entry 5xvq

View 5xvq on RCSB PDB site
Description: Crystal structure of monkey Nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl Nicotinamide (MNA)
Class: transferase
Keywords: NNMT, MNA, ternary complex, feedback inhibition, T2D, TRANSFERASE
Deposited on 2017-06-28, released 2017-08-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-08-02, with a file datestamp of 2017-07-28.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nicotinamide N-methyltransferase (NNMT)
    Species: Macaca mulatta [TaxId:9544]
    Gene: NNMT, EGK_06915
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5xvqa_
  • Chain 'B':
    Compound: Nicotinamide N-methyltransferase (NNMT)
    Species: Macaca mulatta [TaxId:9544]
    Gene: NNMT, EGK_06915
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5xvqb_
  • Heterogens: SAH, 8GC, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5xvqA (A:)
mgsshhhhhhssglvprgshmesgftskdtylrhfnprdylekyykfgsrhsaesqilkh
llenlfkifcldgvkgdllidigsgptiyqllsacesfkeiivtdysdqnlqelekwlkk
epeafdwspvvtyvcdlegnrvkgpekeeklrqavkqvlkcdvtqsqplgavplpladcl
lstlcldaacpdlptyrralrnlgsllkpggflvimdalkssyymigeqkfsslplgrea
veaavkeagytiewfevisqsysstmanneglfslvgrklsrsl

    Sequence, based on observed residues (ATOM records): (download) 
    >5xvqA (A:)
ftskdtylrhfnprdylekyyksaesqilkhllenlfkifcldgvkgdllidigsgptiy
qllsacesfkeiivtdysdqnlqelekwlkkepeafdwspvvtyvcdlegnrvkgpekee
klrqavkqvlkcdvtqsqplgavplpladcllstlcldaacpdlptyrralrnlgsllkp
ggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfevisqsysstmann
eglfslvgrkls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5xvqB (B:)
mgsshhhhhhssglvprgshmesgftskdtylrhfnprdylekyykfgsrhsaesqilkh
llenlfkifcldgvkgdllidigsgptiyqllsacesfkeiivtdysdqnlqelekwlkk
epeafdwspvvtyvcdlegnrvkgpekeeklrqavkqvlkcdvtqsqplgavplpladcl
lstlcldaacpdlptyrralrnlgsllkpggflvimdalkssyymigeqkfsslplgrea
veaavkeagytiewfevisqsysstmanneglfslvgrklsrsl

    Sequence, based on observed residues (ATOM records): (download) 
    >5xvqB (B:)
ftskdtylrhfnprdylekyyksaesqilkhllenlfkifcldgvkgdllidigsgptiy
qllsacesfkeiivtdysdqnlqelekwlkkepeafdwspvvtyvcdlegnrvkgpekee
klrqavkqvlkcdvtqsqplgavplpladcllstlcldaacpdlptyrralrnlgsllkp
ggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfevisqsysstmann
eglfslvgrkls