PDB entry 5xve
View 5xve on RCSB PDB site
Description: Crystal structure of human USP2 C276S mutant in complex with ubiquitin
Class: hydrolase
Keywords: ubiquitin specific protease for anticancer target, HYDROLASE
Deposited on
2017-06-27, released
2018-02-28
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-02-28, with a file datestamp of
2018-02-23.
Experiment type: XRAY
Resolution: 1.24 Å
R-factor: N/A
AEROSPACI score: 0.63
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ubiquitin carboxyl-terminal hydrolase 2
Species: Homo sapiens [TaxId:9606]
Gene: USP2, UBP41
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5xvea_ - Chain 'B':
Compound: Ubiquitin-40S ribosomal protein S27a
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5xveb_ - Heterogens: ZN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5xveA (A:)
mnsksaqglaglrnlgntsfmnsilqclsntrelrdyclqrlymrdlhhgsnahtalvee
fakliqtiwtsspndvvspsefktqiqryaprfvgynqqdaqeflrflldglhnevnrvt
lrpksnpenldhlpddekgrqmwrkyleredsrigdlfvgqlkssltctdcgycstvfdp
fwdlslpiakrgypevtlmdcmrlftkedvldgdekptccrcrgrkrcikkfsiqrfpki
lvlhlkrfsesrirtsklttfvnfplrdldlrefasentnhavynlyavsnhsgttmggh
ytaycrspgtgewhtfndssvtpmsssqvrtsdayllfyelasppsrmlehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>5xveA (A:)
aqglaglrnlgntsfmnsilqclsntrelrdyclqrlymrdlhhgsnahtalveefakli
qtiwtsspndvvspsefktqiqryaprfvgynqqdaqeflrflldglhnevnrvtlenld
hlpddekgrqmwrkyleredsrigdlfvgqlkssltctdcgycstvfdpfwdlslpiakr
gypevtlmdcmrlftkedvldgdekptccrcrgrkrcikkfsiqrfpkilvlhlkrfses
rirtsklttfvnfplrdldlrefasentnhavynlyavsnhsgttmgghytaycrspgtg
ewhtfndssvtpmsssqvrtsdayllfyela
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>5xveB (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg