PDB entry 5xuq

View 5xuq on RCSB PDB site
Description: Crystal structure of VDR-LBD complexed with an antagonist, 2-methylidene-19,26,27-trinor-22-(S)-butyl-1-hydroxy-25-oxo-25-(1H-pyrrol-2-yl)- vitamin D3
Class: transcription
Keywords: Vitamin D receptor antagonist helix 10/11, TRANSCRIPTION
Deposited on 2017-06-24, released 2018-06-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-06-27, with a file datestamp of 2018-06-22.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Vitamin D3 receptor
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Vdr, Nr1i1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5xuqa_
  • Chain 'C':
    Compound: Mediator of RNA polymerase II transcription subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: MED1, ARC205, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 8FF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5xuqA (A:)
gshmgspnsplkdslrpklseeqqhiiailldahhktydptyadfrdfrppvrmdgstgs
vtldlsplsmlphladlvsysiqkvigfakmipgfrdltsddqivllkssaievimlrsn
qsftmddmswdcgsqdykydvtdvskaghtlelieplikfqvglkklnlheeehvllmai
civspdrpgvqdaklveaiqdrlsntlqtyircrhpppgshqlyakmiqkladlrslnee
hskqyrslsfqpensmkltplvlevfgneis

    Sequence, based on observed residues (ATOM records): (download) 
    >5xuqA (A:)
klseeqqhiiailldahhktydptyadfrdfrppvrsplsmlphladlvsysiqkvigfa
kmipgfrdltsddqivllkssaievimlrsnqsftmddmswdcgsqdykydvtdvskagh
tlelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaklveaiqdrlsntlqt
yircrhpppgshqlyakmiqkladlrslneehskqpensmkltplvlevfg

  • Chain 'C':
    No sequence available.