PDB entry 5xlv

View 5xlv on RCSB PDB site
Description: Mycobacterium tuberculosis Pantothenate kinase mutant F254A
Class: transferase
Keywords: Homodimer, CoA biosynthesis, Nucleotide binding, Concerted movement, Structural transformation, TRANSFERASE
Deposited on 2017-05-11, released 2018-05-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-12-05, with a file datestamp of 2018-11-30.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pantothenate kinase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: coaA, Rv1092c, MTV017.45c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WPA7 (Start-311)
      • engineered mutation (253)
    Domains in SCOPe 2.08: d5xlva_
  • Chain 'B':
    Compound: pantothenate kinase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: coaA, Rv1092c, MTV017.45c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5xlvb_
  • Heterogens: SO4, PG4, EDO, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5xlvA (A:)
msrlsepspyvefdrrqwralrmstplalteeelvglrglgeqidlleveevylplarli
hlqvaarqrlfaataeflgepqqnpdrpvpfiigvagsvavgksttarvlqallarwdhh
prvdlvttdgflypnaelqrrnlmhrkgfpesynrralmrfvtsvksgsdyacapvyshl
hydiipgaeqvvrhpdilileglnvlqtgptlmvsdlfdfslyvdariedieqwyvsrfl
amrttafadpeshahhyaafsdsqavvaareiwrtinrpnlvenilptrpratlvlrkda
dhsinrlrlrkl

    Sequence, based on observed residues (ATOM records): (download) 
    >5xlvA (A:)
pspyvefdrrqwralrmstplalteeelvglrglgeqidlleveevylplarlihlqvaa
rqrlfaataeflgepqqnpdrpvpfiigvagsvavgksttarvlqallarwdhhprvdlv
ttdgflypnaelqrrnlmhrkgfpesynrralmrfvtsvksgsdyacapvyshlhydiip
gaeqvvrhpdilileglnvlqtgptlmvsdlfdfslyvdariedieqwyvsrflamrtta
fadpeshahhyaafsdsqavvaareiwrtinrpnlvenilptrpratlvlrkdadhsinr
lrlrkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5xlvB (B:)
msrlsepspyvefdrrqwralrmstplalteeelvglrglgeqidlleveevylplarli
hlqvaarqrlfaataeflgepqqnpdrpvpfiigvagsvavgksttarvlqallarwdhh
prvdlvttdgflypnaelqrrnlmhrkgfpesynrralmrfvtsvksgsdyacapvyshl
hydiipgaeqvvrhpdilileglnvlqtgptlmvsdlfdfslyvdariedieqwyvsrfl
amrttafadpeshahhyaafsdsqavvaareiwrtinrpnlvenilptrpratlvlrkda
dhsinrlrlrkl

    Sequence, based on observed residues (ATOM records): (download) 
    >5xlvB (B:)
pspyvefdrrqwralrmstplalteeelvglrglgeqidlleveevylplarlihlqvaa
rqrlfaataeflgepqqnpdrpvpfiigvagsvavgksttarvlqallarwdhhprvdlv
ttdgflypnaelqrrnlmhrkgfpesynrralmrfvtsvksgsdyacapvyshlhydiip
gaeqvvrhpdilileglnvlqtgptlmvsdlfdfslyvdariedieqwyvsrflamrdsq
avvaareiwrtinrpnlvenilptrpratlvlrkdadhsinrlrlrkl