PDB entry 5x8k

View 5x8k on RCSB PDB site
Description: V158T mutant of thermus thermophilus HB8 thymidylate kinase
Class: transferase
Keywords: Nucleotide monophosphate kinase, TRANSFERASE
Deposited on 2017-03-03, released 2018-03-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-11-21, with a file datestamp of 2018-11-16.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [TaxId:300852]
    Gene: tmk, TTHA1607
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SHX3
      • engineered mutation (157)
    Domains in SCOPe 2.08: d5x8ka_
  • Chain 'B':
    Compound: thymidylate kinase
    Species: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [TaxId:300852]
    Gene: tmk, TTHA1607
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SHX3
      • engineered mutation (157)
    Domains in SCOPe 2.08: d5x8kb_
  • Heterogens: NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5x8kA (A:)
mpglfltlegldgsgkttqarrlaafleaqgrpvlltrepggglpevrsllltqelspea
eyllfsadraehvrkvilpglaagkvvisdryldsslayqgygrglplpwlrevareatr
glkprltflldlppeaalrrvrrpdrleglgleffrrtregylalaraepgrfvvldatl
peeeiaraiqahlrpllp

    Sequence, based on observed residues (ATOM records): (download) 
    >5x8kA (A:)
pglfltlegldgsgkttqarrlaafleaqgrpvlltrepggglpevrsllltqelspeae
yllfsadraehvrkvilpglaagkvvisdryldsslayqgygrglplpwlrevareatrg
lkprltflldlppeaaglgleffrrtregylalaraepgrfvvldatlpeeeiaraiqah
lrpll

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5x8kB (B:)
mpglfltlegldgsgkttqarrlaafleaqgrpvlltrepggglpevrsllltqelspea
eyllfsadraehvrkvilpglaagkvvisdryldsslayqgygrglplpwlrevareatr
glkprltflldlppeaalrrvrrpdrleglgleffrrtregylalaraepgrfvvldatl
peeeiaraiqahlrpllp

    Sequence, based on observed residues (ATOM records): (download) 
    >5x8kB (B:)
pglfltlegldgsgkttqarrlaafleaqgrpvlltrepggglpevrsllltqelspeae
yllfsadraehvrkvilpglaagkvvisdryldsslayqgygrglplpwlrevareatrg
lkprltflldlppeaagleffrrtregylalaraepgrfvvldatlpeeeiaraiqahlr
pll