SCOPe 2.06: Structural Classification of Proteins

PDB entry 5x2t

View 5x2t on RCSB PDB site
Description: Direct Observation of Conformational Population Shifts in Hemoglobin: Crystal Structure of Half-Liganded Hemoglobin after Adding 4 mM bezafibrate pH 7.2.
Class: transport protein
Keywords: Hemoglobin, Allostery, Allosteric proteins, Oxygen binding, Bezafibrate, TRANSPORT PROTEIN
Deposited on 2017-02-02, released 2017-09-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 2.64 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Hemoglobin subunit alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P69905 (Start-140)
Domains in SCOPe 2.06: d5x2ta_
Chain 'B':
Compound: Hemoglobin subunit beta
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P68871 (Start-145)
Domains in SCOPe 2.06: d5x2tb_
Chain 'C':
Compound: Hemoglobin subunit alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P69905 (Start-140)
Domains in SCOPe 2.06: d5x2tc_
Chain 'D':
Compound: Hemoglobin subunit beta
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P68871 (Start-145)
Domains in SCOPe 2.06: d5x2td_
Chain 'E':
Compound: Hemoglobin subunit alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P69905 (Start-140)
Domains in SCOPe 2.06: d5x2te_
Chain 'F':
Compound: Hemoglobin subunit beta
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P68871 (Start-145)
Domains in SCOPe 2.06: d5x2tf_
Chain 'G':
Compound: Hemoglobin subunit alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P69905 (Start-140)
Domains in SCOPe 2.06: d5x2tg_
Chain 'H':
Compound: Hemoglobin subunit beta
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P68871 (Start-145)
Domains in SCOPe 2.06: d5x2th_
Chain 'I':
Compound: Hemoglobin subunit alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P69905 (Start-140)
Domains in SCOPe 2.06: d5x2ti_
Chain 'J':
Compound: Hemoglobin subunit beta
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P68871 (Start-145)
Domains in SCOPe 2.06: d5x2tj_
Chain 'K':
Compound: Hemoglobin subunit alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P69905 (Start-140)
Domains in SCOPe 2.06: d5x2tk_
Chain 'L':
Compound: Hemoglobin subunit beta
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P68871 (Start-145)
Domains in SCOPe 2.06: d5x2tl_
Heterogens: HNI, HEM, PEM

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>5x2tA (A:)
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr