PDB entry 5wk3

View 5wk3 on RCSB PDB site
Description: crystal structure of the complex between ccl17 and m116 fab
Class: immune system
Keywords: immune system
Deposited on 2017-07-24, released 2017-12-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-03, with a file datestamp of 2017-12-29.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: C-C motif chemokine 17
    Species: Homo sapiens [TaxId:9606]
    Gene: CCL17, SCYA17, TARC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wk3a_
  • Chain 'B':
    Compound: C-C motif chemokine 17
    Species: Homo sapiens [TaxId:9606]
    Gene: CCL17, SCYA17, TARC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wk3b_
  • Chain 'C':
    Compound: C-C motif chemokine 17
    Species: Homo sapiens [TaxId:9606]
    Gene: CCL17, SCYA17, TARC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wk3c_
  • Chain 'D':
    Compound: C-C motif chemokine 17
    Species: Homo sapiens [TaxId:9606]
    Gene: CCL17, SCYA17, TARC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wk3d_
  • Chain 'P':
    Compound: m116 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WK3 (0-End)
    Domains in SCOPe 2.08: d5wk3p1, d5wk3p2
  • Chain 'Q':
    Compound: m116 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WK3 (0-End)
    Domains in SCOPe 2.08: d5wk3q_
  • Chain 'R':
    Compound: m116 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WK3 (0-End)
    Domains in SCOPe 2.08: d5wk3r1, d5wk3r2
  • Chain 'S':
    Compound: m116 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WK3 (0-End)
    Domains in SCOPe 2.08: d5wk3s_
  • Chain 'T':
    Compound: m116 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WK3 (0-End)
    Domains in SCOPe 2.08: d5wk3t1, d5wk3t2
  • Chain 'U':
    Compound: m116 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WK3 (0-End)
    Domains in SCOPe 2.08: d5wk3u_
  • Chain 'V':
    Compound: m116 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WK3
    Domains in SCOPe 2.08: d5wk3v1, d5wk3v2
  • Chain 'W':
    Compound: m116 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WK3 (0-End)
    Domains in SCOPe 2.08: d5wk3w_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5wk3A (A:)
argtnvtreccleyfkgaiplrklktwyqtsedcsrdaivfvtvqgraicsdpnnkrvkn
avkylqslers

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3A (A:)
eccleyfkgaiplrklktwyqtsedcsrdaivfvtvqgraicsdpnnkrvknavkylqsl
er

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5wk3B (B:)
argtnvtreccleyfkgaiplrklktwyqtsedcsrdaivfvtvqgraicsdpnnkrvkn
avkylqslers

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3B (B:)
eccleyfkgaiplrklktwyqtsedcsrdaivfvtvqgraicsdpnnkrvknavkylqsl
ers

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5wk3C (C:)
argtnvtreccleyfkgaiplrklktwyqtsedcsrdaivfvtvqgraicsdpnnkrvkn
avkylqslers

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3C (C:)
treccleyfkgaiplrklktwyqtsedcsrdaivfvtvqgraicsdpnnkrvknavkylq
sler

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5wk3D (D:)
argtnvtreccleyfkgaiplrklktwyqtsedcsrdaivfvtvqgraicsdpnnkrvkn
avkylqslers

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3D (D:)
ccleyfkgaiplrklktwyqtsedcsrdaivfvtvqgraicsdpnnkrvknavkylqsle
r

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >5wk3P (P:)
divmtqspdslavslgeratinckssqsvllspwnsnqlawyqqkpgqppklliygastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyylipstfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3P (P:)
divmtqspdslavslgeratinckssqsvllspwnsnqlawyqqkpgqppklliygastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyylipstfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnr

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >5wk3Q (Q:)
evqlvqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiidpsdsdtry
spsfqgqvtisadksistaylqwsslkasdtamyycarvgpadvwdsfdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3Q (Q:)
evqlvqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiidpsdsdtry
spsfqgqvtisadksistaylqwsslkasdtamyycarvgpadvwdsfdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >5wk3R (R:)
divmtqspdslavslgeratinckssqsvllspwnsnqlawyqqkpgqppklliygastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyylipstfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3R (R:)
divmtqspdslavslgeratinckssqsvllspwnsnqlawyqqkpgqppklliygastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyylipstfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnr

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >5wk3S (S:)
evqlvqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiidpsdsdtry
spsfqgqvtisadksistaylqwsslkasdtamyycarvgpadvwdsfdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3S (S:)
evqlvqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiidpsdsdtry
spsfqgqvtisadksistaylqwsslkasdtamyycarvgpadvwdsfdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >5wk3T (T:)
divmtqspdslavslgeratinckssqsvllspwnsnqlawyqqkpgqppklliygastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyylipstfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3T (T:)
divmtqspdslavslgeratinckssqsvllspwnsnqlawyqqkpgqppklliygastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyylipstfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrg

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >5wk3U (U:)
evqlvqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiidpsdsdtry
spsfqgqvtisadksistaylqwsslkasdtamyycarvgpadvwdsfdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3U (U:)
evqlvqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiidpsdsdtry
spsfqgqvtisadksistaylqwsslkasdtamyycarvgpadvwdsfdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'V':
    Sequence, based on SEQRES records: (download) 
    >5wk3V (V:)
divmtqspdslavslgeratinckssqsvllspwnsnqlawyqqkpgqppklliygastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyylipstfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3V (V:)
ivmtqspdslavslgeratinckssqsvllspwnsnqlawyqqkpgqppklliygastre
sgvpdrfsgsgsgtdftltisslqaedvavyycqqyylipstfgqgtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnr

  • Chain 'W':
    Sequence, based on SEQRES records: (download) 
    >5wk3W (W:)
evqlvqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiidpsdsdtry
spsfqgqvtisadksistaylqwsslkasdtamyycarvgpadvwdsfdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wk3W (W:)
evqlvqsgaevkkpgeslkisckgsgysftsywigwvrqmpgkglewmgiidpsdsdtry
spsfqgqvtisadksistaylqwsslkasdtamyycarvgpadvwdsfdywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvep