PDB entry 5wa9
View 5wa9 on RCSB PDB site
Description: Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) H112N mutant nucleoside D-Ala phosphoramidate substrate complex
Class: hydrolase
Keywords: histidine triad, HYDROLASE
Deposited on
2017-06-26, released
2017-10-18
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-11-22, with a file datestamp of
2017-11-17.
Experiment type: XRAY
Resolution: 1.15 Å
R-factor: N/A
AEROSPACI score: 0.68
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Histidine triad nucleotide-binding protein 1
Species: Homo sapiens [TaxId:9606]
Gene: HINT1, HINT, PKCI1, PRKCNH1
Database cross-references and differences (RAF-indexed):
- Uniprot P49773 (Start-128)
- engineered mutation (114)
Domains in SCOPe 2.08: d5wa9a_ - Chain 'B':
Compound: Histidine triad nucleotide-binding protein 1
Species: Homo sapiens [TaxId:9606]
Gene: HINT1, HINT, PKCI1, PRKCNH1
Database cross-references and differences (RAF-indexed):
- Uniprot P49773 (Start-128)
- engineered mutation (114)
Domains in SCOPe 2.08: d5wa9b_ - Heterogens: 9ZD, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5wa9A (A:)
snamadeiakaqvarpggdtifgkiirkeipakiifeddrclafhdispqapthflvipk
khisqisvaedddesllghlmivgkkcaadlglnkgyrmvvnegsdggqsvyhvnlhvlg
grqmhwppg
Sequence, based on observed residues (ATOM records): (download)
>5wa9A (A:)
rpggdtifgkiirkeipakiifeddrclafhdispqapthflvipkkhisqisvaeddde
sllghlmivgkkcaadlglnkgyrmvvnegsdggqsvyhvnlhvlggrqmhwppg
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5wa9B (B:)
snamadeiakaqvarpggdtifgkiirkeipakiifeddrclafhdispqapthflvipk
khisqisvaedddesllghlmivgkkcaadlglnkgyrmvvnegsdggqsvyhvnlhvlg
grqmhwppg
Sequence, based on observed residues (ATOM records): (download)
>5wa9B (B:)
gdtifgkiirkeipakiifeddrclafhdispqapthflvipkkhisqisvaedddesll
ghlmivgkkcaadlglnkgyrmvvnegsdggqsvyhvnlhvlggrqmhwppg