PDB entry 5w85

View 5w85 on RCSB PDB site
Description: crystal structure of irak-4 with a 4,6-diaminonicotinamide inhibitor (compound number 9)
Class: transferase/transferase inhibitor
Keywords: serine/threonine protein kinase, transferase, transferase-transferase inhibitor complex
Deposited on 2017-06-21, released 2017-10-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5w85a_
  • Chain 'B':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5w85b_
  • Heterogens: 9YS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5w85A (A:)
gamgvsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkkl
aamvditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrls
cldgtpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglara
sekfaqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepql
lldikeeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllq
emtas

    Sequence, based on observed residues (ATOM records): (download) 
    >5w85A (A:)
rfhsfsfyelknvtnnfderpisvggnkmgegfgvvykgyvnnttvavkkleelkqqfdq
eikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrckia
qgaanginflhenhhihrdiksanilldeaftakisdfglarastvmtsrivgttaymap
ealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkk
mndadstsveamysvasqclhekknkrpdikkvqqllqemt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5w85B (B:)
gamgvsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkkl
aamvditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrls
cldgtpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglara
sekfaqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepql
lldikeeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllq
emtas

    Sequence, based on observed residues (ATOM records): (download) 
    >5w85B (B:)
rfhsfsfyelknvtnnfderpisvggnkmgefgvvykgyvnnttvavkkleelkqqfdqe
ikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrckiaq
gaanginflhenhhihrdiksanilldeaftakisdfglarasqtvmtsrivgttaymap
ealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkk
mndadstsveamysvasqclhekknkrpdikkvqqllqemta