PDB entry 5w84

View 5w84 on RCSB PDB site
Description: crystal structure of irak-4 with a 4,6-diaminonicotinamide inhibitor (compound number 4)
Class: transferase/transferase inhibitor
Keywords: serine/threonine protein kinase, transferase, transferase-transferase inhibitor complex
Deposited on 2017-06-21, released 2017-10-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5w84a_
  • Chain 'B':
    Compound: interleukin-1 receptor-associated kinase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: Irak4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5w84b_
  • Heterogens: 9YY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5w84A (A:)
gamgvsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkkl
aamvditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrls
cldgtpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglara
sekfaqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepql
lldikeeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllq
emtas

    Sequence, based on observed residues (ATOM records): (download) 
    >5w84A (A:)
fhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklittkqqfdq
eikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrckia
qgaanginflhenhhihrdiksanilldeaftakisdfglarastvmtsrivgttaymap
ealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkk
mndadstsveamysvasqclhekknkrpdikkvqqllqemta

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5w84B (B:)
gamgvsdtrfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkkl
aamvditteelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrls
cldgtpplswhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglara
sekfaqtvmtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepql
lldikeeiedeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllq
emtas

    Sequence, based on observed residues (ATOM records): (download) 
    >5w84B (B:)
fsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkdqeikvmakcqhen
lvellgfsclvyvympngslldrlscldgtpplswhmrckiaqgaanginflhenhhihr
diksanilldeaftakisdfglarastvmtsrivgttaymapealrgeitpksdiysfgv
vlleiitglpavdehrepqllldikeeiedeektiedyidkkmndadstsveamysvasq
clhekknkrpdikkvqqllqemta