PDB entry 5vq8

View 5vq8 on RCSB PDB site
Description: Crystal structure of human WT-KRAS in complex with GDP (EDTA soaked)
Class: hydrolase
Keywords: hydrolase
Deposited on 2017-05-08, released 2017-12-06
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-12-06, with a file datestamp of 2017-12-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (1-End)
      • expression tag (0)
      • engineered mutation (118)
    Domains in SCOPe 2.06: d5vq8a1, d5vq8a2
  • Chain 'B':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (1-End)
      • expression tag (0)
      • engineered mutation (118)
    Domains in SCOPe 2.06: d5vq8b1, d5vq8b2
  • Heterogens: GDP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5vq8A (A:)
    hmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
    gqeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnksd
    lpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhkek
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vq8A (A:)
    hmteyklvvvgaggvgksaltiqliqnhfvdeydsyrkqvvidgetclldildtmrdqym
    rtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnksdlpsrtvdtkqaqd
    larsygipfietsaktrqgvddafytlvreirkhke
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5vq8B (B:)
    hmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
    gqeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnksd
    lpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhkek
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vq8B (B:)
    hmteyklvvvgaggvgksaltiqliqnhfvdeydsyrkqvvidgetclldildtmrdqym
    rtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnksdlpsrtvdtkqaqd
    larsygipfietsaktrqgvddafytlvreirkhke