PDB entry 5vig

View 5vig on RCSB PDB site
Description: Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII
Class: immune system
Keywords: antibody, Fab, Zika, Dengue, recurrent, neutralizing, immune system
Deposited on 2017-04-16, released 2017-05-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-05-17, with a file datestamp of 2017-05-12.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5VIG (Start-111)
    • Uniprot S6B291 (112-End)
    Domains in SCOPe 2.08: d5viga_
  • Chain 'B':
    Compound: Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5VIG (0-106)
    • Uniprot P0DOX7 (107-End)
    Domains in SCOPe 2.08: d5vigb1, d5vigb2
  • Chain 'G':
    Compound: Zika virus envelope protein DIII
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5vigg_
  • Chain 'H':
    Compound: Fab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5VIG (Start-111)
    • Uniprot S6B291 (112-End)
    Domains in SCOPe 2.08: d5vigh_
  • Chain 'L':
    Compound: Fab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5VIG (0-106)
    • Uniprot P0DOX7 (107-End)
    Domains in SCOPe 2.08: d5vigl1, d5vigl2
  • Chain 'Z':
    Compound: Zika virus envelope protein DIII
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5vigz_
  • Heterogens: FLC

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5vigA (A:)
evqllesggglvqpggslrlscaasgftfknyamawvrqapgkglewvsllynseestyy
adsvkgrftisrdnskntlflqmnrlrvedtavyfcvrdrsngwssinlwgrgtlvtvss
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5vigA (A:)
vqllesggglvqpggslrlscaasgftfknyamawvrqapgkglewvsllynseestyya
dsvkgrftisrdnskntlflqmnrlrvedtavyfcvrdrsngwssinlwgrgtlvtvssa
stkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5vigB (B:)
diqmtqspstlsasvgdrvtmtcrasqtisgwlawyqqkpgkapklliyqasrlesgips
rfsgsgsgteftltisslqpddvatyycqqystfwtfglgtkveikrtvaapsvfifpps
deqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltl
skadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5vigB (B:)
diqmtqspstlsasvgdrvtmtcrasqtisgwlawyqqkpgkapklliyqasrlesgips
rfsgsgsgteftltisslqpddvatyycqqystfwtfglgtkveikrtvaapsvfifpps
deqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltl
skadyekhkvyacevthqglsspvtksfnrge

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5vigG (G:)
mrlkgvsyslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgr
litanpvitestenskmmleldppfgdsyivigvgekkithhwhrsgsti

    Sequence, based on observed residues (ATOM records): (download) 
    >5vigG (G:)
yslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgrlitanpv
itestenskmmleldppfgdsyivigvgekkithhwhrsg

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5vigH (H:)
evqllesggglvqpggslrlscaasgftfknyamawvrqapgkglewvsllynseestyy
adsvkgrftisrdnskntlflqmnrlrvedtavyfcvrdrsngwssinlwgrgtlvtvss
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5vigH (H:)
vqllesggglvqpggslrlscaasgftfknyamawvrqapgkglewvsllynseestyya
dsvkgrftisrdnskntlflqmnrlrvedtavyfcvrdrsngwssinlwgrgtlvtvssa
stkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >5vigL (L:)
diqmtqspstlsasvgdrvtmtcrasqtisgwlawyqqkpgkapklliyqasrlesgips
rfsgsgsgteftltisslqpddvatyycqqystfwtfglgtkveikrtvaapsvfifpps
deqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltl
skadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5vigL (L:)
diqmtqspstlsasvgdrvtmtcrasqtisgwlawyqqkpgkapklliyqasrlesgips
rfsgsgsgteftltisslqpddvatyycqqystfwtfglgtkveikrtvaapsvfifpps
deqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstltl
skadyekhkvyacevthqglsspvtksfnrge

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >5vigZ (Z:)
mrlkgvsyslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgr
litanpvitestenskmmleldppfgdsyivigvgekkithhwhrsgsti

    Sequence, based on observed residues (ATOM records): (download) 
    >5vigZ (Z:)
yslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgrlitanpv
itestenskmmleldppfgdsyivigvgekkithhwhrsg