PDB entry 5uwm

View 5uwm on RCSB PDB site
Description: Matrix metalloproteinase-13 complexed with selective inhibitor compound (R)-17a
Class: hydrolase/hydrolase inhibitor
Keywords: Metalloproteinase, collagenase, MMP-13, hydrolase, hydrolase-hydrolase inhibitor complex
Deposited on 2017-02-21, released 2017-07-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-07-26, with a file datestamp of 2017-07-21.
Experiment type: XRAY
Resolution: 1.62 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5uwma_
  • Chain 'B':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5uwmb_
  • Chain 'C':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5UWM (0-4)
  • Chain 'D':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5UWM (Start-4)
  • Heterogens: ZN, CA, 8OA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5uwmA (A:)
mynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiad
imisfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaah
efghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgdedpn

    Sequence, based on observed residues (ATOM records): (download) 
    >5uwmA (A:)
lkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimisfgik
ehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefghslgl
dhskdpgalmfpiytythfmlpdddvqgiqslygp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5uwmB (B:)
mynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiad
imisfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaah
efghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgdedpn

    Sequence, based on observed residues (ATOM records): (download) 
    >5uwmB (B:)
lkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimisfgik
ehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefghslgl
dhskdpgalmfpiytyfmlpdddvqgiqslygpg

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.