PDB entry 5uqq

View 5uqq on RCSB PDB site
Description: Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus
Class: transferase
Keywords: mcsA, 2-methylcitrate synthase, citrate synthase, TRANSFERASE
Deposited on 2017-02-08, released 2018-02-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-06-17, with a file datestamp of 2020-06-12.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-methylcitrate synthase, mitochondrial
    Species: Neosartorya fumigata [TaxId:746128]
    Gene: mcsA, cit1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5uqqa_
  • Chain 'B':
    Compound: 2-methylcitrate synthase, mitochondrial
    Species: Neosartorya fumigata [TaxId:746128]
    Gene: mcsA, cit1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5uqqb_
  • Chain 'C':
    Compound: 2-methylcitrate synthase, mitochondrial
    Species: Neosartorya fumigata [TaxId:746128]
    Gene: mcsA, cit1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5uqqc_
  • Chain 'D':
    Compound: 2-methylcitrate synthase, mitochondrial
    Species: Neosartorya fumigata [TaxId:746128]
    Gene: mcsA, cit1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5uqqd_
  • Chain 'E':
    Compound: 2-methylcitrate synthase, mitochondrial
    Species: Neosartorya fumigata [TaxId:746128]
    Gene: mcsA, cit1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5uqqe_
  • Chain 'F':
    Compound: 2-methylcitrate synthase, mitochondrial
    Species: Neosartorya fumigata [TaxId:746128]
    Gene: mcsA, cit1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5uqqf_
  • Heterogens: SRT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5uqqA (A:)
mhhhhhhssgvdlgtenlyfqsgsgstaepdlktalkavipakrelfkqvkersdevige
vkvanviggmrglksmlwegsvldpeegirfhgktikdcqkelpkgtsgtemlpeamfwl
lltgqvpstnqvrafsrelaeqshlpqhildliksfprsmhpmtqlsiavaalnteskfa
kayekglskadyweptfddsisllakiprvaalvfrpdevdqvgtqaldasqdwsynfae
llgkggkenqdfhdllrlylalhgdheggnvsahathlvgsalsdpflsysagllglagp
lhglaaqevlrwilamqdkigtkftdddvrnylwdtlksgrvvpgyghgvlrkpdprfqa
lmdfaatrpdvlanpvfqlvkknseiapavltehgktknphpnvdaasgvlfyhygfqqp
lyytvtfgvsralgplvqliwdralglpierpksinllglkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5uqqA (A:)
aepdlktalkavipakrelfkqvkersdevigevkvanviggmrglksmlwegsvldpee
girfhgktikdcqkelpkgtsgtemlpeamfwllltgqvpstnqvrafsrelaeqshlpq
hildliksfprsmhpmtqlsiavaalnteskfakayekglskadyweptfddsisllaki
prvaalvfrpdevdqvgtqaldasqdwsynfaellgkggkenqdfhdllrlylalhgdhe
ggnvsahathlvgsalsdpflsysagllglagplhglaaqevlrwilamqdkigtkftdd
dvrnylwdtlksgrvvpgyghgvlrkpdprfqalmdfaatrpdvlanpvfqlvkknseia
pavltehgktknphpnvdaasgvlfyhygfqqplyytvtfgvsralgplvqliwdralgl
pierpksinllglkk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5uqqB (B:)
mhhhhhhssgvdlgtenlyfqsgsgstaepdlktalkavipakrelfkqvkersdevige
vkvanviggmrglksmlwegsvldpeegirfhgktikdcqkelpkgtsgtemlpeamfwl
lltgqvpstnqvrafsrelaeqshlpqhildliksfprsmhpmtqlsiavaalnteskfa
kayekglskadyweptfddsisllakiprvaalvfrpdevdqvgtqaldasqdwsynfae
llgkggkenqdfhdllrlylalhgdheggnvsahathlvgsalsdpflsysagllglagp
lhglaaqevlrwilamqdkigtkftdddvrnylwdtlksgrvvpgyghgvlrkpdprfqa
lmdfaatrpdvlanpvfqlvkknseiapavltehgktknphpnvdaasgvlfyhygfqqp
lyytvtfgvsralgplvqliwdralglpierpksinllglkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5uqqB (B:)
taepdlktalkavipakrelfkqvkersdevigevkvanviggmrglksmlwegsvldpe
egirfhgktikdcqkelpkgtsgtemlpeamfwllltgqvpstnqvrafsrelaeqshlp
qhildliksfprsmhpmtqlsiavaalnteskfakayekglskadyweptfddsisllak
iprvaalvfrpdevdqvgtqaldasqdwsynfaellgkggkenqdfhdllrlylalhgdh
eggnvsahathlvgsalsdpflsysagllglagplhglaaqevlrwilamqdkigtkftd
ddvrnylwdtlksgrvvpgyghgvlrkpdprfqalmdfaatrpdvlanpvfqlvkknsei
apavltehgktknphpnvdaasgvlfyhygfqqplyytvtfgvsralgplvqliwdralg
lpierpksinllglkk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5uqqC (C:)
mhhhhhhssgvdlgtenlyfqsgsgstaepdlktalkavipakrelfkqvkersdevige
vkvanviggmrglksmlwegsvldpeegirfhgktikdcqkelpkgtsgtemlpeamfwl
lltgqvpstnqvrafsrelaeqshlpqhildliksfprsmhpmtqlsiavaalnteskfa
kayekglskadyweptfddsisllakiprvaalvfrpdevdqvgtqaldasqdwsynfae
llgkggkenqdfhdllrlylalhgdheggnvsahathlvgsalsdpflsysagllglagp
lhglaaqevlrwilamqdkigtkftdddvrnylwdtlksgrvvpgyghgvlrkpdprfqa
lmdfaatrpdvlanpvfqlvkknseiapavltehgktknphpnvdaasgvlfyhygfqqp
lyytvtfgvsralgplvqliwdralglpierpksinllglkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5uqqC (C:)
staepdlktalkavipakrelfkqvkersdevigevkvanviggmrglksmlwegsvldp
eegirfhgktikdcqkelpkgtsgtemlpeamfwllltgqvpstnqvrafsrelaeqshl
pqhildliksfprsmhpmtqlsiavaalnteskfakayekglskadyweptfddsislla
kiprvaalvfrpdevdqvgtqaldasqdwsynfaellgkggkenqdfhdllrlylalhgd
heggnvsahathlvgsalsdpflsysagllglagplhglaaqevlrwilamqdkigtkft
dddvrnylwdtlksgrvvpgyghgvlrkpdprfqalmdfaatrpdvlanpvfqlvkknse
iapavltehgktknphpnvdaasgvlfyhygfqqplyytvtfgvsralgplvqliwdral
glpierpksinllglkk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5uqqD (D:)
mhhhhhhssgvdlgtenlyfqsgsgstaepdlktalkavipakrelfkqvkersdevige
vkvanviggmrglksmlwegsvldpeegirfhgktikdcqkelpkgtsgtemlpeamfwl
lltgqvpstnqvrafsrelaeqshlpqhildliksfprsmhpmtqlsiavaalnteskfa
kayekglskadyweptfddsisllakiprvaalvfrpdevdqvgtqaldasqdwsynfae
llgkggkenqdfhdllrlylalhgdheggnvsahathlvgsalsdpflsysagllglagp
lhglaaqevlrwilamqdkigtkftdddvrnylwdtlksgrvvpgyghgvlrkpdprfqa
lmdfaatrpdvlanpvfqlvkknseiapavltehgktknphpnvdaasgvlfyhygfqqp
lyytvtfgvsralgplvqliwdralglpierpksinllglkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5uqqD (D:)
aepdlktalkavipakrelfkqvkersdevigevkvanviggmrglksmlwegsvldpee
girfhgktikdcqkelpkgtsgtemlpeamfwllltgqvpstnqvrafsrelaeqshlpq
hildliksfprsmhpmtqlsiavaalnteskfakayekglskadyweptfddsisllaki
prvaalvfrpdevdqvgtqaldasqdwsynfaellgkggkenqdfhdllrlylalhgdhe
ggnvsahathlvgsalsdpflsysagllglagplhglaaqevlrwilamqdkigtkftdd
dvrnylwdtlksgrvvpgyghgvlrkpdprfqalmdfaatrpdvlanpvfqlvkknseia
pavltehgktknphpnvdaasgvlfyhygfqqplyytvtfgvsralgplvqliwdralgl
pierpksinllglk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5uqqE (E:)
mhhhhhhssgvdlgtenlyfqsgsgstaepdlktalkavipakrelfkqvkersdevige
vkvanviggmrglksmlwegsvldpeegirfhgktikdcqkelpkgtsgtemlpeamfwl
lltgqvpstnqvrafsrelaeqshlpqhildliksfprsmhpmtqlsiavaalnteskfa
kayekglskadyweptfddsisllakiprvaalvfrpdevdqvgtqaldasqdwsynfae
llgkggkenqdfhdllrlylalhgdheggnvsahathlvgsalsdpflsysagllglagp
lhglaaqevlrwilamqdkigtkftdddvrnylwdtlksgrvvpgyghgvlrkpdprfqa
lmdfaatrpdvlanpvfqlvkknseiapavltehgktknphpnvdaasgvlfyhygfqqp
lyytvtfgvsralgplvqliwdralglpierpksinllglkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5uqqE (E:)
aepdlktalkavipakrelfkqvkersdevigevkvanviggmrglksmlwegsvldpee
girfhgktikdcqkelpkgtsgtemlpeamfwllltgqvpstnqvrafsrelaeqshlpq
hildliksfprsmhpmtqlsiavaalnteskfakayekglskadyweptfddsisllaki
prvaalvfrpdevdqvgtqaldasqdwsynfaellgkggkenqdfhdllrlylalhgdhe
ggnvsahathlvgsalsdpflsysagllglagplhglaaqevlrwilamqdkigtkftdd
dvrnylwdtlksgrvvpgyghgvlrkpdprfqalmdfaatrpdvlanpvfqlvkknseia
pavltehgktknphpnvdaasgvlfyhygfqqplyytvtfgvsralgplvqliwdralgl
pierpksinllglk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5uqqF (F:)
mhhhhhhssgvdlgtenlyfqsgsgstaepdlktalkavipakrelfkqvkersdevige
vkvanviggmrglksmlwegsvldpeegirfhgktikdcqkelpkgtsgtemlpeamfwl
lltgqvpstnqvrafsrelaeqshlpqhildliksfprsmhpmtqlsiavaalnteskfa
kayekglskadyweptfddsisllakiprvaalvfrpdevdqvgtqaldasqdwsynfae
llgkggkenqdfhdllrlylalhgdheggnvsahathlvgsalsdpflsysagllglagp
lhglaaqevlrwilamqdkigtkftdddvrnylwdtlksgrvvpgyghgvlrkpdprfqa
lmdfaatrpdvlanpvfqlvkknseiapavltehgktknphpnvdaasgvlfyhygfqqp
lyytvtfgvsralgplvqliwdralglpierpksinllglkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5uqqF (F:)
aepdlktalkavipakrelfkqvkersdevigevkvanviggmrglksmlwegsvldpee
girfhgktikdcqkelpkgtsgtemlpeamfwllltgqvpstnqvrafsrelaeqshlpq
hildliksfprsmhpmtqlsiavaalnteskfakayekglskadyweptfddsisllaki
prvaalvfrpdevdqvgtqaldasqdwsynfaellgkggkenqdfhdllrlylalhgdhe
ggnvsahathlvgsalsdpflsysagllglagplhglaaqevlrwilamqdkigtkftdd
dvrnylwdtlksgrvvpgyghgvlrkpdprfqalmdfaatrpdvlanpvfqlvkknseia
pavltehgktknphpnvdaasgvlfyhygfqqplyytvtfgvsralgplvqliwdralgl
pierpksinllglkk