PDB entry 5ulu

View 5ulu on RCSB PDB site
Description: Crystal Structure of Mouse Cadherin-23 EC19-21 (S2087P) with non-syndromic deafness (DFNB12) associated mutation D2148N
Class: cell adhesion
Keywords: hearing, mechanotransduction, adhesion, calcium-binding protein, CELL ADHESION
Deposited on 2017-01-25, released 2018-01-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cadherin-23
    Species: Mus musculus [TaxId:10090]
    Gene: Cdh23
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99PF4
      • engineered mutation (133)
      • engineered mutation (194)
    Domains in SCOPe 2.08: d5ulua1, d5ulua2, d5ulua3
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5uluA (A:)
mnhplftegtyqaevmenspagtpltvlngpilaldadedvyavvtyqllgthsdlfvid
nstgvvtvrsgiiidreafsppflellllaedigqlngtahlfitilddndnwptfsppt
ytvhllencppgfpvlqvtatdedsglngelvyrieagaqdrflihpvtgvirvgnatid
reeqesyrltvvatnrgtvplsgtaivtiliddindsrpeflnpiqtvsvlesaepgtii
anvtaidldlnpkleyhiisivakddtdrlvpdqedafavnintgsvmvksplnrelvat
yevtlsvidnasdlpehsvsvpnakltvnildvndnlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5uluA (A:)
plftegtyqaevmenspagtpltvlngpilalvtyqllgthsdlfvidnstgvvtvrsgi
iidreafsppflellllaedigqlngtahlfitilddndnwptfspptytvhllencppg
fpvlqvtatdedsglngelvyrieagaqdrflihpvtgvirvgnatidreeqesyrltvv
atnrgtvplsgtaivtiliddindsrpeflnpiqtvsvlesaepgtiianvtaidldlnp
kleyhiisivakddtdrlvpdqedafavnintgsvmvksplnrelvatyevtlsvidnas
dlpehsvsvpnakltvnild