PDB entry 5ujb

View 5ujb on RCSB PDB site
Description: Structure of a Mcl-1 Inhibitor Binding to Site 3 of Human Serum Albumin
Class: transport protein
Keywords: Human Serum Albumin, Free fraction, Apoptosis, cancer, Mcl-1, drug discovery, TRANSPORT PROTEIN
Deposited on 2017-01-17, released 2017-05-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-13, with a file datestamp of 2017-09-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serum albumin
    Species: Homo sapiens [TaxId:9606]
    Gene: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ujba1, d5ujba2, d5ujba3
  • Chain 'B':
    Compound: serum albumin
    Species: Homo sapiens [TaxId:9606]
    Gene: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ujbb1, d5ujbb2, d5ujbb3
  • Heterogens: 6AK, PO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5ujbA (A:)
    mkwvtfisllflfssaysrgvfrrdahksevahrfkdlgeenfkalvliafaqylqqcpf
    edhvklvnevtefaktcvadesaencdkslhtlfgdklctvatlretygemadccakqep
    ernecflqhkddnpnlprlvrpevdvmctafhdneetflkkylyeiarrhpyfyapellf
    fakrykaafteccqaadkaacllpkldelrdegkassakqrlkcaslqkfgerafkawav
    arlsqrfpkaefaevsklvtdltkvhtecchgdllecaddradlakyicenqdsissklk
    eccekpllekshciaevendempadlpslaadfveskdvcknyaeakdvflgmflyeyar
    rhpdysvvlllrlaktyettlekccaaadphecyakvfdefkplveepqnlikqncelfe
    qlgeykfqnallvrytkkvpqvstptlvevsrnlgkvgskcckhpeakrmpcaedylsvv
    lnqlcvlhektpvsdrvtkccteslvnrrpcfsalevdetyvpkefnaetftfhadictl
    sekerqikkqtalvelvkhkpkatkeqlkavmddfaafvekcckaddketcfaeegkklv
    aasqaalgl
    

    Sequence, based on observed residues (ATOM records): (download)
    >5ujbA (A:)
    ksevahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesaencd
    kslhtlfgdklctvatlretygemadccakqepernecflqhkddnpnlprlvrpevdvm
    ctafhdneetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllpkld
    elrdegkassakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltkvht
    ecchgdllecaddradlakyicenqdsissklkeccekpllekshciaevendempadlp
    slaadfveskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekccaa
    adphecyakvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvstptl
    vevsrnlgkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkccteslvn
    rrpcfsalevdetyvpkefnaetftfhadictlsekerqikkqtalvelvkhkpkatkeq
    lkavmddfaafvekcckaddketcfaee
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5ujbB (B:)
    mkwvtfisllflfssaysrgvfrrdahksevahrfkdlgeenfkalvliafaqylqqcpf
    edhvklvnevtefaktcvadesaencdkslhtlfgdklctvatlretygemadccakqep
    ernecflqhkddnpnlprlvrpevdvmctafhdneetflkkylyeiarrhpyfyapellf
    fakrykaafteccqaadkaacllpkldelrdegkassakqrlkcaslqkfgerafkawav
    arlsqrfpkaefaevsklvtdltkvhtecchgdllecaddradlakyicenqdsissklk
    eccekpllekshciaevendempadlpslaadfveskdvcknyaeakdvflgmflyeyar
    rhpdysvvlllrlaktyettlekccaaadphecyakvfdefkplveepqnlikqncelfe
    qlgeykfqnallvrytkkvpqvstptlvevsrnlgkvgskcckhpeakrmpcaedylsvv
    lnqlcvlhektpvsdrvtkccteslvnrrpcfsalevdetyvpkefnaetftfhadictl
    sekerqikkqtalvelvkhkpkatkeqlkavmddfaafvekcckaddketcfaeegkklv
    aasqaalgl
    

    Sequence, based on observed residues (ATOM records): (download)
    >5ujbB (B:)
    ksevahrfkdlgeenfkalvliafaqylqqcpfedhvklvnevtefaktcvadesaencd
    kslhtlfgdklctvatlretygemadccakqepernecflqhkddnpnlprlvrpevdvm
    ctafhdneetflkkylyeiarrhpyfyapellffakrykaafteccqaadkaacllpkld
    elrdegkassakqrlkcaslqkfgerafkawavarlsqrfpkaefaevsklvtdltkvht
    ecchgdllecaddradlakyicenqdsissklkeccekpllekshciaevendempadlp
    slaadfveskdvcknyaeakdvflgmflyeyarrhpdysvvlllrlaktyettlekccaa
    adphecyakvfdefkplveepqnlikqncelfeqlgeykfqnallvrytkkvpqvstptl
    vevsrnlgkvgskcckhpeakrmpcaedylsvvlnqlcvlhektpvsdrvtkccteslvn
    rrpcfsalevdetyvpkefnaetftfhadictlsekerqikkqtalvelvkhkpkatkeq
    lkavmddfaafvekcckaddketcf