PDB entry 5u6q

View 5u6q on RCSB PDB site
Description: Structure of human MR1-3-F-SA in complex with human MAIT A-F7 TCR
Class: immune system
Keywords: T-cell receptor, MHC-like molecule, IMMUNE SYSTEM
Deposited on 2016-12-08, released 2017-02-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-270)
      • initiating methionine (0)
      • conflict (261)
    Domains in SCOPe 2.07: d5u6qa1, d5u6qa2, d5u6qa3
  • Chain 'B':
    Compound: MAIT T-cell receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRAV/TRAC
    Database cross-references and differences (RAF-indexed):
    • PDB 5U6Q
    Domains in SCOPe 2.07: d5u6qb1, d5u6qb2
  • Chain 'C':
    Compound: Major histocompatibility complex class I-related gene protein
    Species: Homo sapiens [TaxId:9606]
    Gene: MR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q95460 (1-End)
      • initiating methionine (0)
      • conflict (261)
    Domains in SCOPe 2.07: d5u6qc1, d5u6qc2, d5u6qc3
  • Chain 'D':
    Compound: MAIT T-cell receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRAV/TRAC
    Database cross-references and differences (RAF-indexed):
    • PDB 5U6Q (0-End)
    Domains in SCOPe 2.07: d5u6qd1, d5u6qd2
  • Chain 'E':
    Compound: MAIT T-cell receptor beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRBV/TRBC
    Database cross-references and differences (RAF-indexed):
    • PDB 5U6Q (0-End)
    Domains in SCOPe 2.07: d5u6qe1, d5u6qe2
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5u6qf_
  • Chain 'G':
    Compound: MAIT T-cell receptor beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TRBV/TRBC
    Database cross-references and differences (RAF-indexed):
    • PDB 5U6Q
    Domains in SCOPe 2.07: d5u6qg1, d5u6qg2
  • Chain 'H':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5u6qh_
  • Heterogens: 7ZS, GOL, ACT, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5u6qA (A:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
    awasieldpqssnlyschvehsgvhmvlqvp
    

    Sequence, based on observed residues (ATOM records): (download)
    >5u6qA (A:)
    mrthslryfrlgvsdpivpefisvgyvdshpittydsvtrqkeprapwmaenlapdhwer
    ytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdfli
    fnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrtep
    plvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqaw
    asiellyschvehsgvhmvlqvp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5u6qB (B:)
    gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
    ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
    lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
    acanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >5u6qB (B:)
    qnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrfs
    sflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyql
    rdsksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfacana
    fnnsiipedtffpsp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5u6qC (C:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnrketfpgvtalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyq
    awasieldpqssnlyschvehsgvhmvlqvp
    

    Sequence, based on observed residues (ATOM records): (download)
    >5u6qC (C:)
    mrthslryfrlgvsdpihgvpefisvgyvdshpittydsvtrqkeprapwmaenlapdhw
    erytqllrgwqqmfkvelkrlqrhynhsgshtyqrmigcelledgsttgflqyaydgqdf
    lifnkdtlswlavdnvahtikqaweanqhellyqknwleeeciawlkrfleygkdtlqrt
    epplvrvnalfckahgfyppeiymtwmkngeeivqeidygdilpsgdgtyqawasieldp
    qssnlyschvehsgvhmvlqv
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5u6qD (D:)
    gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
    ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
    lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
    acanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records): (download)
    >5u6qD (D:)
    gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
    ssflsrskgysylllkelqmkdsasylcavkdsnyqliwgagtkliikpdiqnpdpavyq
    lrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdf
    acanafnnsiipedtffpsp
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >5u6qE (E:)
    nagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgev
    pngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlkn
    vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
    qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
    wgrad
    

    Sequence, based on observed residues (ATOM records): (download)
    >5u6qE (E:)
    nagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgev
    pngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlkn
    vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
    qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
    wgra
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >5u6qF (F:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records): (download)
    >5u6qF (F:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdr
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >5u6qG (G:)
    nagvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgev
    pngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlkn
    vfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplke
    qpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaea
    wgrad
    

    Sequence, based on observed residues (ATOM records): (download)
    >5u6qG (G:)
    agvtqtpkfqvlktgqsmtlqcaqdmnhnsmywyrqdpgmglrliyysasegttdkgevp
    ngynvsrlnkrefslrlesaapsqtsvyfcassvwtgegsgelffgegsrltvledlknv
    fppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeq
    palndsryalssrlrvsatfwqnfrcqvqfyglsendewtqdrakpvtqivsaeawgra
    

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5u6qH (H:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm