PDB entry 5tsr

View 5tsr on RCSB PDB site
Description: Crystal structure of PRL-3 phosphatase in complex with the Bateman domain of CNNM3 magnesium transporter
Class: metal transport
Keywords: phosphatase, magnesium transporter, protein binding, METAL TRANSPORT
Deposited on 2016-10-31, released 2017-02-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-02-08, with a file datestamp of 2017-02-03.
Experiment type: XRAY
Resolution: 3.19 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein tyrosine phosphatase type IVA 3
    Species: Homo sapiens [TaxId:9606]
    Gene: PTP4A3, PRL3
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75365
      • engineered mutation (106)
    Domains in SCOPe 2.06: d5tsra_
  • Chain 'B':
    Compound: Metal transporter CNNM3
    Species: Homo sapiens [TaxId:9606]
    Gene: CNNM3, ACDP3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NE01 (11-End)
      • expression tag (0-10)
  • Chain 'C':
    Compound: Protein tyrosine phosphatase type IVA 3
    Species: Homo sapiens [TaxId:9606]
    Gene: PTP4A3, PRL3
    Database cross-references and differences (RAF-indexed):
    • Uniprot O75365
      • engineered mutation (106)
    Domains in SCOPe 2.06: d5tsrc_
  • Chain 'D':
    Compound: Metal transporter CNNM3
    Species: Homo sapiens [TaxId:9606]
    Gene: CNNM3, ACDP3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NE01 (11-End)
      • expression tag (0-10)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5tsrA (A:)
gshmarmnrpapvevsykhmrflithnptnatlstfiedlkkygattvvrvcevtydktp
lekdgitvvdwpfddgapppgkvvedwlslvkakfceapgscvavhavaglgrapvlval
aliesgmkyedaiqfirqkrrgainskqltylekyrpkqrlrfkdphthktr

    Sequence, based on observed residues (ATOM records): (download) 
    >5tsrA (A:)
nrpapvevsykhmrflithnptnatlstfiedlkkygattvvrvcevtydktplekdgit
vvdwpfddgapppgkvvedwlslvkakfceapgscvavhavaglgrapvlvalaliesgm
kyedaiqfirqkrrgainskqltylekyrpkqrlr

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5tsrC (C:)
gshmarmnrpapvevsykhmrflithnptnatlstfiedlkkygattvvrvcevtydktp
lekdgitvvdwpfddgapppgkvvedwlslvkakfceapgscvavhavaglgrapvlval
aliesgmkyedaiqfirqkrrgainskqltylekyrpkqrlrfkdphthktr

    Sequence, based on observed residues (ATOM records): (download) 
    >5tsrC (C:)
nrpapvevsykhmrflithnptnatlstfiedlkkygattvvrvcevtydktplekdgit
vvdwpfddgapppgkvvedwlslvkakfceapgscvavhavaglgrapvlvalaliesgm
kyedaiqfirqkrrgainskqltylekyrpkqrl

  • Chain 'D':
    No sequence available.