PDB entry 5tr4
View 5tr4 on RCSB PDB site
Description: Structure of Ubiquitin activating enzyme (Uba1) in complex with ubiquitin and TAK-243
Class: ligase/ligase inhibitor
Keywords: LIGASE-LIGASE INHIBITOR complex
Deposited on
2016-10-25, released
2017-11-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-11-01, with a file datestamp of
2017-10-27.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ubiquitin-activating enzyme E1 1
Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
Gene: UBA1, YKL210W
Database cross-references and differences (RAF-indexed):
- Uniprot P22515 (Start-1016)
- engineered mutation (463)
- engineered mutation (511)
- Chain 'B':
Compound: Ubiquitin
Species: Bos taurus [TaxId:9913]
Gene: UBB
Database cross-references and differences (RAF-indexed):
- Uniprot P0CG53 (0-75)
- conflict (18)
- conflict (23)
- conflict (27)
Domains in SCOPe 2.08: d5tr4b_ - Chain 'C':
Compound: Ubiquitin-activating enzyme E1 1
Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
Gene: UBA1, YKL210W
Database cross-references and differences (RAF-indexed):
- Uniprot P22515 (Start-1016)
- engineered mutation (463)
- engineered mutation (511)
- Chain 'D':
Compound: Ubiquitin
Species: Bos taurus [TaxId:9913]
Gene: UBB
Database cross-references and differences (RAF-indexed):
- Uniprot P0CG53 (0-75)
- conflict (18)
- conflict (23)
- conflict (27)
Domains in SCOPe 2.08: d5tr4d_ - Heterogens: 61T, HOH