PDB entry 5t36

View 5t36 on RCSB PDB site
Description: Crystal structure of mPGES-1 bound to inhibitor
Class: membrane protein
Keywords: prostaglandin, enzyme, integral membrane protein, alpha helix, MEMBRANE PROTEIN
Deposited on 2016-08-24, released 2017-03-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prostaglandin E synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: PTGES, MGST1L1, MPGES1, PGES, PIG12
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5t36a_
  • Heterogens: 755, GSH, BOG, PG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5t36A (A:)
malpahslvmsspalpafllcstllvikmyvvaiitgqvrlrkkafanpedalrhggpqy
crsdpdverclrahrndmetiypflflgfvysflgpnpfvawmhflvflvgrvahtvayl
gklrapirsvtytlaqlpcasmalqilweaarhl

    Sequence, based on observed residues (ATOM records): (download) 
    >5t36A (A:)
lvmsspalpafllcstllvikmyvvaiitgqvrlrkkafanpedalrhggpqycrsdpdv
erclrahrndmetiypflflgfvysflgpnpfvawmhflvflvgrvahtvaylgklrapi
rsvtytlaqlpcasmalqilweaarhl