PDB entry 5sxp
View 5sxp on RCSB PDB site
Description: structural basis for the interaction between itch prr and beta-pix
Class: signaling protein/ligase
Keywords: SH3 DOMAIN PEPTIDE LIGAND COMPLEX, LIGASE, SIGNALING PROTEIN-LIGASE complex
Deposited on
2016-08-09, released
2017-03-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-01-08, with a file datestamp of
2020-01-03.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Rho guanine nucleotide exchange factor 7
Species: Homo sapiens [TaxId:9606]
Gene: ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB, Nbla10314
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5sxpa_ - Chain 'B':
Compound: Rho guanine nucleotide exchange factor 7
Species: Homo sapiens [TaxId:9606]
Gene: ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB, Nbla10314
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5sxpb_ - Chain 'C':
Compound: Rho guanine nucleotide exchange factor 7
Species: Homo sapiens [TaxId:9606]
Gene: ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB, Nbla10314
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5sxpc_ - Chain 'D':
Compound: Rho guanine nucleotide exchange factor 7
Species: Homo sapiens [TaxId:9606]
Gene: ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB, Nbla10314
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5sxpd_ - Chain 'F':
Compound: E3 ubiquitin-protein ligase Itchy homolog
Species: Homo sapiens [TaxId:9606]
Gene: ITCH
Database cross-references and differences (RAF-indexed):
- Chain 'G':
Compound: E3 ubiquitin-protein ligase Itchy homolog
Species: Homo sapiens [TaxId:9606]
Gene: ITCH
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5sxpA (A:)
gsnnqlvvrakfnfqqtnedelsfskgdvihvtrveeggwwegtlngrtgwfpsnyvrev
ka
Sequence, based on observed residues (ATOM records): (download)
>5sxpA (A:)
snnqlvvrakfnfqqtnedelsfskgdvihvtrveeggwwegtlngrtgwfpsnyvrevk
a
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5sxpB (B:)
gsnnqlvvrakfnfqqtnedelsfskgdvihvtrveeggwwegtlngrtgwfpsnyvrev
ka
Sequence, based on observed residues (ATOM records): (download)
>5sxpB (B:)
snnqlvvrakfnfqqtnedelsfskgdvihvtrveeggwwegtlngrtgwfpsnyvrevk
a
- Chain 'C':
Sequence, based on SEQRES records: (download)
>5sxpC (C:)
gsnnqlvvrakfnfqqtnedelsfskgdvihvtrveeggwwegtlngrtgwfpsnyvrev
ka
Sequence, based on observed residues (ATOM records): (download)
>5sxpC (C:)
nnqlvvrakfnfqqtnedelsfskgdvihvtrveeggwwegtlngrtgwfpsnyvrevka
- Chain 'D':
Sequence, based on SEQRES records: (download)
>5sxpD (D:)
gsnnqlvvrakfnfqqtnedelsfskgdvihvtrveeggwwegtlngrtgwfpsnyvrev
ka
Sequence, based on observed residues (ATOM records): (download)
>5sxpD (D:)
nnqlvvrakfnfqqtnedelsfskgdvihvtrveeggwwegtlngrtgwfpsnyvrevka
- Chain 'F':
No sequence available.
- Chain 'G':
No sequence available.