PDB entry 5pb5
View 5pb5 on RCSB PDB site
Description: human factor VIIa in complex with 1-[[3-[5-hydroxy-4-(7H-pyrrolo[2,3-d]pyrimidin-6-yl)pyrazol-1-yl]phenyl]methyl]-3-phenylurea at 1.84A
Class: hydrolase/hydrolase inhibitor
Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex
Deposited on
2016-11-16, released
2017-06-21
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-02-21, with a file datestamp of
2018-02-16.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Coagulation factor VII light chain
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5pb5a_ - Chain 'B':
Compound: Coagulation factor VII heavy chain
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5pb5b_ - Heterogens: GOL, 9RY, CA, CL, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5pb5A (A:)
licvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekrnask
pqgr
Sequence, based on observed residues (ATOM records): (download)
>5pb5A (A:)
icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekrna
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5pb5B (B:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp
Sequence, based on observed residues (ATOM records): (download)
>5pb5B (B:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrniteymfcagysdgskd
sckgdsggphathyrgtwyltgivswggcatvghfgvytrvsqyiewlqklmrseprpgv
llrapfp