PDB entry 5paw
View 5paw on RCSB PDB site
Description: Crystal Structure of Factor VIIa in complex with isoquinoline-1,6-diamine
Class: hydrolase/hydrolase inhibitor
Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex
Deposited on
2016-11-10, released
2017-06-21
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-02-21, with a file datestamp of
2018-02-16.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Coagulation factor VII light chain
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5pawa_ - Chain 'B':
Compound: Coagulation factor VII heavy chain
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5pawb_ - Heterogens: CL, CA, SO4, 7XM, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5pawA (A:)
licvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekrnask
pqgr
Sequence, based on observed residues (ATOM records): (download)
>5pawA (A:)
licvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5pawB (B:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp
Sequence, based on observed residues (ATOM records): (download)
>5pawB (B:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrspniteymfcagysdgs
kdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrsepr
pgvllrapfp