PDB entry 5pac
View 5pac on RCSB PDB site
Description: human factor VIIa in complex with 5-hydroxy-N-(4-oxo-3H-quinazolin-6-yl)-1-[3-[(phenylcarbamoylamino)methyl]phenyl]pyrazole-4-carboxamide at 1.50A
Class: hydrolase/hydrolase inhibitor
Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex
Deposited on
2016-11-10, released
2017-06-21
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-06-21, with a file datestamp of
2017-06-16.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Coagulation factor VII light chain
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d5paca_ - Chain 'B':
Compound: Coagulation factor VII heavy chain
Species: Homo sapiens [TaxId:9606]
Gene: F7
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d5pacb_ - Heterogens: GOL, 7Y7, CA, CL, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5pacA (A:)
licvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekrnask
pqgr
Sequence, based on observed residues (ATOM records): (download)
>5pacA (A:)
icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekrna
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5pacB (B:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp
Sequence, based on observed residues (ATOM records): (download)
>5pacB (B:)
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsniteymfcagysdgskds
ckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrseprpgv
llrapfp