PDB entry 5omh

View 5omh on RCSB PDB site
Description: p38alpha in complex with pyrazolobenzothiazine inhibitor COXH11
Class: transferase
Keywords: p38, kinase, inhibitor, pyrazolobenzothiazine, complex, Transferase
Deposited on 2017-07-31, released 2019-03-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-03, with a file datestamp of 2019-03-29.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5omha_
  • Heterogens: 9Y5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5omhA (A:)
msqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemt
gyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvg
tpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaa
qalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >5omhA (A:)
rptfyrqelnktiwevperyqnlspvygsvcaafdtktglrvavkklsrpfqsiihakrt
yrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnkltddhvqfliyq
ilrglkyihsadiihrdlkpsnlavnedcelkildatrwyrapeimlnwmhynqtvdiws
vgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltqmpkm
nfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadpydqsfe
srdllidewksltydevisfvpppl