PDB entry 5ohk

View 5ohk on RCSB PDB site
Description: Crystal structure of USP30 in covalent complex with ubiquitin propargylamide (high resolution)
Class: hydrolase
Keywords: Deubiquitinase, DUB, Ubiquitin, USP, HYDROLASE
Deposited on 2017-07-17, released 2017-09-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.34 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30
    Species: Homo sapiens [TaxId:9606]
    Gene: usp30
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q70CQ3 (2-116)
      • linker (117-120)
    • Uniprot Q70CQ3 (121-261)
      • engineered mutation (252)
      • engineered mutation (254)
      • engineered mutation (257)
      • linker (262-264)
    • Uniprot Q70CQ3 (265-335)
    Domains in SCOPe 2.08: d5ohka_
  • Chain 'B':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ohkb_
  • Heterogens: AYE, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ohkA (A:)
gpkglvpglvnlgntcfmnsllqglsacpafirwleeftsqysrdqkeppshqylsltll
hllkalscqevtddevldasclldvlrmyrwqissfeeqdahelfhvitsslederdgsg
shwksqhpfhgrltsnmvckhcehqspvrfdtfdslslsipaatwghpltldhclhhfis
sesvrdvvcdnctkieakgtlngekvehqrttfvkqlklgklpqclcihlqrlswsshgt
plkrhehvqfnedlsmdeykyhsnastylfrlmavvvhhgdmhsghfvtyrrsppsarnp
lstsnqwlwvsddtvrkaslqevlsssayllfyerv

    Sequence, based on observed residues (ATOM records): (download) 
    >5ohkA (A:)
kglvpglvnlgntcfmnsllqglsacpafirwleeftsqysrqylsltllhllkalscqe
vtddevldasclldvlrmyrwqissfeeqdahelfhvitsslederdgsgshwksqhpfh
grltsnmvckhcehqspvrfdtfdslslsipaatwghpltldhclhhfissesvrdvvcd
nctkrttfvkqlklgklpqclcihlqrlswsshgtplkrhehvqfnedlsmdeykyhsna
stylfrlmavvvhhgdmhsghfvtyrrsppssnqwlwvsddtvrkaslqevlsssayllf
yerv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ohkB (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgx

    Sequence, based on observed residues (ATOM records): (download) 
    >5ohkB (B:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrg