PDB entry 5neu

View 5neu on RCSB PDB site
Description: Localised Reconstruction of Integrin alpha v beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose B
Class: virus
Keywords: Foot and Mouth Disease Virus, FMDV, virus, OpanAsia, virus-receptor, complex
Deposited on 2017-03-11, released 2017-06-21
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-06-21, with a file datestamp of 2017-06-16.
Experiment type: EM
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: O1 Manisa VP1
    Species: Foot-and-mouth disease virus [TaxId:12110]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5neu1_
  • Chain '2':
    Compound: O1 Manisa VP2
    Species: Foot-and-mouth disease virus [TaxId:12110]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6PMW3 (Start-217)
      • engineered mutation (92)
  • Chain '3':
    Compound: capsid protein
    Species: Foot-and-mouth disease virus [TaxId:12110]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1C6ZW60 (0-219)
      • conflict (167)
      • conflict (173)
    Domains in SCOPe 2.06: d5neu3_
  • Chain '4':
    Compound: O1 Manisa VP4
    Species: Foot-and-mouth disease virus [TaxId:12110]
    Database cross-references and differences (RAF-indexed):
  • Chain 'A':
    Compound: Integrin alpha-V
    Species: Homo sapiens [TaxId:9606]
    Gene: ITGAV, MSK8, VNRA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06756 (0-589)
      • conflict (397)
    Domains in SCOPe 2.06: d5neua1, d5neua2
  • Chain 'B':
    Compound: integrin beta-6
    Species: Homo sapiens [TaxId:9606]
    Gene: ITGB6
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18564 (0-469)
      • conflict (265)
      • conflict (447)
  • Heterogens: MG, CA

PDB Chain Sequences:

  • Chain '1':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5neu1 (1:)
    ttsagesadpvtatvenyggetqvqrrqhtdvsfildrfvkvtpkdqinvldlmqtpaht
    lvgallrtatyyfadlevavkhegnltwvpngapeaaldnttnptayhkapltrlalpyt
    aphrvlatvyngnskygdgtvanvrgdlqvlaqkaaralptsfnygaikatrvtellyrm
    kraetycprpllaihpdqarhkqkivap
    

  • Chain '2':
    No sequence available.

  • Chain '3':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5neu3 (3:)
    gifpvacsdgygglvttdpktadpaygkvfnpprnmlpgrftnfldvaeacptflhfegd
    vpyvttktdsdrvlaqfdlslaakhmsntflaglaqyytqysgtinlhfmftgptdakar
    ymiayappgmeppktpeaaahcihaewdtglnskftfsipylsaadytytasdvaettnv
    qgwvclfqithgkadgdalvvlasagkdfelrlpvdartq
    

  • Chain '4':
    No sequence available.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5neuA (A:)
    fnldvdspaeysgpegsyfgfavdffvpssrmfllvgapkanttqpgiveggqvlkcdws
    strrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkqer
    epvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywqgq
    lisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfvsg
    vpraartlgmvyiydgknmsslynftgeqmaayfgfsvaatdingddyadvfigaplfmd
    rgsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiaiaa
    pyggedkkgivyifngrstglnavpsqilegqwaarscppsfgysmkgatdidkngypdl
    ivgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclkad
    gkgvlprklnfqvellldklkgairralflysrspshsknmtisrgglmqceeliaylrd
    esefrdkltpitifmeyrldyrtaadttglqpilnqftpanisrqahill
    

  • Chain 'B':
    No sequence available.