PDB entry 5nbq

View 5nbq on RCSB PDB site
Description: The structure of the tripartite complex between OspE, the C-terminal domains of factor H and C3dg
Class: immune system
Keywords: complement, regulation, microbe, evasion, immune system
Deposited on 2017-03-02, released 2017-12-06
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-12-06, with a file datestamp of 2017-12-01.
Experiment type: XRAY
Resolution: 3.18 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Complement C3
    Species: Homo sapiens [TaxId:9606]
    Gene: C3, CPAMD1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01024
      • engineered mutation (16)
    Domains in SCOPe 2.06: d5nbqa_
  • Chain 'B':
    Compound: Complement C3
    Species: Homo sapiens [TaxId:9606]
    Gene: C3, CPAMD1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01024 (Start-293)
      • engineered mutation (16)
    Domains in SCOPe 2.06: d5nbqb_
  • Chain 'C':
    Compound: Complement C3
    Species: Homo sapiens [TaxId:9606]
    Gene: C3, CPAMD1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01024 (0-End)
      • engineered mutation (16)
    Domains in SCOPe 2.06: d5nbqc_
  • Chain 'D':
    Compound: complement factor h
    Species: Homo sapiens [TaxId:9606]
    Gene: CFH, HF, HF1, HF2
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: complement factor h
    Species: Homo sapiens [TaxId:9606]
    Gene: CFH, HF, HF1, HF2
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: complement factor h
    Species: Homo sapiens [TaxId:9606]
    Gene: CFH, HF, HF1, HF2
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Outer surface protein E
    Species: Borreliella burgdorferi [TaxId:139]
    Gene: OspE
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Outer surface protein E,Outer surface protein E
    Species: Borreliella burgdorferi [TaxId:139]
    Gene: OspE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q45001
    • PDB 5NBQ (129-133)
  • Chain 'I':
    Compound: Outer surface protein E
    Species: Borreliella burgdorferi [TaxId:139]
    Gene: OspE
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5nbqA (A:)
avdaerlkhlivtpsgageqnmigmtptviavhyldeteqwekfglekrqgalelikkgy
tqqlafrqpssafaafvkrapstwltayvvkvfslavnliaidsqvlcgavkwlilekqk
pdgvfqedapvihqemigglrnnnekdmaltafvlislqeakdiceeqvnslpgsitkag
dfleanymnlqrsytvaiagyalaqmgrlkgpllnkflttakdknrwedpgkqlynveat
syallallqlkdfdfvppvvrwlneqryygggygstqatfmvfqalaqyqkdap

    Sequence, based on observed residues (ATOM records): (download) 
    >5nbqA (A:)
daerlkhlivtpsgageqnmigmtptviavhyldeteqwekfglekrqgalelikkgytq
qlafrqpssafaafvkrapstwltayvvkvfslavnliaidsqvlcgavkwlilekqkpd
gvfqedapvihqemigglrnnnekdmaltafvlislqeakdiceeqvnslpgsitkagdf
leanymnlqrsytvaiagyalaqmgrlkgpllnkflttakdknrwedpgkqlynveatsy
allallqlkdfdfvppvvrwlneqryygggygstqatfmvfqalaqyqkd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5nbqB (B:)
avdaerlkhlivtpsgageqnmigmtptviavhyldeteqwekfglekrqgalelikkgy
tqqlafrqpssafaafvkrapstwltayvvkvfslavnliaidsqvlcgavkwlilekqk
pdgvfqedapvihqemigglrnnnekdmaltafvlislqeakdiceeqvnslpgsitkag
dfleanymnlqrsytvaiagyalaqmgrlkgpllnkflttakdknrwedpgkqlynveat
syallallqlkdfdfvppvvrwlneqryygggygstqatfmvfqalaqyqkdap

    Sequence, based on observed residues (ATOM records): (download) 
    >5nbqB (B:)
vdaerlkhlivtpsgageqnmigmtptviavhyldeteqwekfglekrqgalelikkgyt
qqlafrqpssafaafvkrapstwltayvvkvfslavnliaidsqvlcgavkwlilekqkp
dgvfqedapvihqemigglrnnnekdmaltafvlislqeakdiceeqvnslpgsitkagd
fleanymnlqrsytvaiagyalaqmgrlkgpllnkflttakdknrwedpgkqlynveats
yallallqlkdfdfvppvvrwlneqryygggygstqatfmvfqalaqyqkdap

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5nbqC (C:)
avdaerlkhlivtpsgageqnmigmtptviavhyldeteqwekfglekrqgalelikkgy
tqqlafrqpssafaafvkrapstwltayvvkvfslavnliaidsqvlcgavkwlilekqk
pdgvfqedapvihqemigglrnnnekdmaltafvlislqeakdiceeqvnslpgsitkag
dfleanymnlqrsytvaiagyalaqmgrlkgpllnkflttakdknrwedpgkqlynveat
syallallqlkdfdfvppvvrwlneqryygggygstqatfmvfqalaqyqkdap

    Sequence, based on observed residues (ATOM records): (download) 
    >5nbqC (C:)
avdaerlkhlivtpsgageqnmigmtptviavhyldeteqwekfglekrqgalelikkgy
tqqlafrqpssafaafvkrapstwltayvvkvfslavnliaidsqvlcgavkwlilekqk
pdgvfqedapvihqemigglrnnnekdmaltafvlislqeakdiceeqvnslpgsitkag
dfleanymnlqrsytvaiagyalaqmgrlkgpllnkflttakdknrwedpgkqlynveat
syallallqlkdfdfvppvvrwlneqryygggygstqatfmvfqalaqyqkda

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    No sequence available.