SCOPe 2.08: Structural Classification of Proteins

PDB entry 5n5v

View 5n5v on RCSB PDB site
Description: Structure of p-boronophenylalanyl tRNA synthetase - apo form
Class: ligase
Keywords: aminoacylation, ligase, non-natural amino acid, synthetic biology
Deposited on 2017-02-14, released 2018-02-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-05-16, with a file datestamp of 2018-05-11.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Tyrosine--tRNA ligase
Species: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [TaxId:243232]
Gene: tyrS, MJ0389
Database cross-references and differences (RAF-indexed):
- Uniprot Q57834 (0-305)
  - engineered mutation (5)
  - engineered mutation (31)
  - engineered mutation (64)
  - engineered mutation (69)
  - engineered mutation (157)
  - engineered mutation (161)
  - engineered mutation (285)
  - expression tag (306-308)
Domains in SCOPe 2.08: d5n5va1, d5n5va2
Chain 'B':
Compound: Tyrosine--tRNA ligase
Species: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [TaxId:243232]
Gene: tyrS, MJ0389
Database cross-references and differences (RAF-indexed):
- Uniprot Q57834 (0-305)
  - engineered mutation (5)
  - engineered mutation (31)
  - engineered mutation (64)
  - engineered mutation (69)
  - engineered mutation (157)
  - engineered mutation (161)
  - engineered mutation (285)
  - expression tag (306)
Domains in SCOPe 2.08: d5n5vb1, d5n5vb2
Chain 'C':
Compound: Tyrosine--tRNA ligase
Species: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [TaxId:243232]
Gene: tyrS, MJ0389
Database cross-references and differences (RAF-indexed):
- Uniprot Q57834 (0-305)
  - engineered mutation (5)
  - engineered mutation (31)
  - engineered mutation (64)
  - engineered mutation (69)
  - engineered mutation (157)
  - engineered mutation (161)
  - engineered mutation (285)
Domains in SCOPe 2.08: d5n5vc_
Chain 'D':
Compound: Tyrosine--tRNA ligase
Species: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [TaxId:243232]
Gene: tyrS, MJ0389
Database cross-references and differences (RAF-indexed):
- Uniprot Q57834 (0-305)
  - engineered mutation (5)
  - engineered mutation (31)
  - engineered mutation (64)
  - engineered mutation (69)
  - engineered mutation (157)
  - engineered mutation (161)
  - engineered mutation (285)
  - expression tag (306-308)
Domains in SCOPe 2.08: d5n5vd1, d5n5vd2
Chain 'E':
Compound: Tyrosine--tRNA ligase
Species: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [TaxId:243232]
Gene: tyrS, MJ0389
Database cross-references and differences (RAF-indexed):
- Uniprot Q57834 (0-305)
  - engineered mutation (5)
  - engineered mutation (31)
  - engineered mutation (64)
  - engineered mutation (69)
  - engineered mutation (157)
  - engineered mutation (161)
  - engineered mutation (285)
  - expression tag (306-308)
Domains in SCOPe 2.08: d5n5ve1, d5n5ve2
Chain 'F':
Compound: Tyrosine--tRNA ligase
Species: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [TaxId:243232]
Gene: tyrS, MJ0389
Database cross-references and differences (RAF-indexed):
- Uniprot Q57834 (0-305)
  - engineered mutation (5)
  - engineered mutation (31)
  - engineered mutation (64)
  - engineered mutation (69)
  - engineered mutation (157)
  - engineered mutation (161)
  - engineered mutation (285)
  - expression tag (306-308)
Domains in SCOPe 2.08: d5n5vf1, d5n5vf2
Chain 'G':
Compound: Tyrosine--tRNA ligase
Species: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [TaxId:243232]
Gene: tyrS, MJ0389
Database cross-references and differences (RAF-indexed):
- Uniprot Q57834 (0-305)
  - engineered mutation (5)
  - engineered mutation (31)
  - engineered mutation (64)
  - engineered mutation (69)
  - engineered mutation (157)
  - engineered mutation (161)
  - engineered mutation (285)
  - expression tag (306-308)
Domains in SCOPe 2.08: d5n5vg1, d5n5vg2
Chain 'H':
Compound: Tyrosine--tRNA ligase
Species: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [TaxId:243232]
Gene: tyrS, MJ0389
Database cross-references and differences (RAF-indexed):
- Uniprot Q57834 (0-305)
  - engineered mutation (5)
  - engineered mutation (31)
  - engineered mutation (64)
  - engineered mutation (69)
  - engineered mutation (157)
  - engineered mutation (161)
  - engineered mutation (285)
  - expression tag (306)
Domains in SCOPe 2.08: d5n5vh1, d5n5vh2
Heterogens: CL, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>5n5vA (A:)
mdefelikrntseiiseeelrevlkkdeksasigfepsgkihlghylqikkmidlqnagf
diiialadlmaylnqkgeldeirkigdynkkvfeamglkakyvygsefqldkdytlnvyr
lalkttlkrarrsmeliaredenpkvaeviypimqvnsihyegvdvavggmeqrkihmla
rellpkkvvcihnpvltgldgegkmssskgnfiavddspeeirakikkaycpagvvegnp
imeiakyfleypltikrpekfggdltvnsyeeleslfknkelhpmrlknavaeelikile
pirkrlsahhhhhh