PDB entry 5moy
View 5moy on RCSB PDB site
Description: Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C
Class: hydrolase
Keywords: beta-helix, vesicles, lumen, toxin, hydrolase, botox
Deposited on
2016-12-14, released
2017-03-15
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-09-06, with a file datestamp of
2017-09-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Botulinum neurotoxin type A
Species: Clostridium botulinum [TaxId:1491]
Gene: botA, atx, bna
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5moya1, d5moya2 - Chain 'B':
Compound: Synaptic vesicle glycoprotein 2C
Species: Homo sapiens [TaxId:9606]
Gene: SV2C, KIAA1054
Database cross-references and differences (RAF-indexed):
- Heterogens: EDO, 2PE, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5moyA (A:)
gsknivntsilsivykkddlidlsrygakinigdrvyydsidknqiklinlesstievil
knaivynsmyenfstsfwikipkyfskinlnneytiinciennsgwkvslnygeiiwtlq
dnkqniqrvvfkysqmvnisdyinrwifvtitnnrltkskiyingrlidqkpisnlgnih
asnkimfkldgcrdprryimikyfnlfdkelnekeikdlydsqsnsgilkdfwgnylqyd
kpyymlnlfdpnkyvdvnnigirgymylkgprgsvvttniylnstlyegtkfiikkyasg
nednivrnndrvyinvvvknkeyrlatnasqagvekilsaleipdvgnlsqvvvmkskdd
qgirnkckmnlqdnngndigfigfhlydniaklvasnwynrqvgkasrtfgcswefipvd
dgwgessl
Sequence, based on observed residues (ATOM records): (download)
>5moyA (A:)
ivntsilsivykkddlidlsrygakinigdrvyydsidknqiklinlesstievilknai
vynsmyenfstsfwikipkyfskinlnneytiinciennsgwkvslnygeiiwtlqdnkq
niqrvvfkysqmvnisdyinrwifvtitnnrltkskiyingrlidqkpisnlgnihasnk
imfkldgcrdprryimikyfnlfdkelnekeikdlydsqsnsgilkdfwgnylqydkpyy
mlnlfdpnkyvdvnnigirgymylkgprgsvvttniylnstlyegtkfiikkyanedniv
rnndrvyinvvvknkeyrlatnasqagvekilsaleipdvgnlsqvvvmksnkckmnlqd
nngndigfigfhlydniaklvasnwynrqvgkasrtfgcswefipvddgwgess
- Chain 'B':
No sequence available.