PDB entry 5mm9

View 5mm9 on RCSB PDB site
Description: VIM-2_2b. Metallo-beta-Lactamase Inhibitors by Bioisosteric Replacement: Preparation, Activity and Binding
Class: hydrolase
Keywords: inhibition properties, bioisosters, thiols, metallo-beta-lactamase inhibitor, hydrolase
Deposited on 2016-12-08, released 2017-03-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-05-10, with a file datestamp of 2017-05-05.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Metallo-beta-lactamase VIM-17
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: blaVIM-17
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5mm9a_
  • Chain 'B':
    Compound: Metallo-beta-lactamase VIM-17
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: blaVIM-17
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5mm9b_
  • Heterogens: ZN, 8SH, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5mm9A (A:)
gvdssgeyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidt
awgakntaallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaev
egneipthsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsr
tsagnvadadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnrsvv
e

    Sequence, based on observed residues (ATOM records): (download) 
    >5mm9A (A:)
eyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgakn
taallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaevegneip
thsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsrtsagnv
adadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnrs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5mm9B (B:)
gvdssgeyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidt
awgakntaallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaev
egneipthsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsr
tsagnvadadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnrsvv
e

    Sequence, based on observed residues (ATOM records): (download) 
    >5mm9B (B:)
eyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgakn
taallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaevegneip
thsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsrtsagnv
adadlaewptsieriqqhypeaqfvipghglpggldllkhttnvvkahtnr