PDB entry 5ml0

View 5ml0 on RCSB PDB site
Description: Bromodomain of Mouse PCAF with (R)-4-chloro-2-methyl-5-((1-methylpiperidin-3-yl)amino)pyridazin-3(2H)-one
Class: transcription
Keywords: INHIBITOR, HISTONE, EPIGENETIC READER, BROMODOMAIN, PCAF, ANTAGONIST, transcription
Deposited on 2016-12-05, released 2017-12-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-12-20, with a file datestamp of 2017-12-15.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone acetyltransferase KAT2B
    Species: Mus musculus [TaxId:10090]
    Gene: KAT2B, PCAF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ml0a_
  • Heterogens: P2L, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ml0A (A:)
sdpeqlystlknilqqvknhpnawpfmepvkrteapgyyevirfpmdlktmserlrnryy
vskklfmadlqrvftnckeynppeseyykcasilekfffskikeaglidk

    Sequence, based on observed residues (ATOM records): (download) 
    >5ml0A (A:)
peqlystlknilqqvknhpnawpfmepvkrteapgyyevirfpmdlktmserlrnryyvs
kklfmadlqrvftnckeynppeseyykcasilekfffskikeaglidk