PDB entry 5lxa

View 5lxa on RCSB PDB site
Description: crystal structure of human adiponectin receptor 2 in complex with a c18 free fatty acid at 3.0 angstrom resolution
Class: membrane protein
Keywords: PROGESTIN AND ADIPOQ RECEPTOR FAMILY, INTEGRAL MEMBRANE PROTEIN, 7TM, CERAMIDASE, membrane protein
Deposited on 2016-09-20, released 2017-03-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-16, with a file datestamp of 2019-10-11.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Adiponectin receptor protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ADIPOR2, PAQR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86V24 (20-End)
      • expression tag (18-19)
  • Chain 'H':
    Compound: Anti-CD30 moab Ki-4 scFv
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 5LXA (0-End)
    Domains in SCOPe 2.08: d5lxah1, d5lxah2
  • Heterogens: ZN, OLA, OLB, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5lxaH (H:)
mgevllqqsgpelvkpgasvritckasgytftdfnmdwvkqspgkslewigdfnpnsggs
iynqkfkdkatftvdkssstaymelrsltfedtavyycaretgtawfaywgqgtlvtvsa
aggggsggggsggggsggggsdiqmtqspaslsasvgetvtitcrasgnihnflawyqqk
qgkspqvlvynaktladgvpsrfsgsgsgtqyslkinslqpedfgsyycqqfwstpytfg
ggtkleinaaaddddkagwshpqfekgggsgggsgggswshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >5lxaH (H:)
mgevllqqsgpelvkpgasvritckasgytftdfnmdwvkqspgkslewigdfnpnsggs
iynqkfkdkatftvdkssstaymelrsltfedtavyycaretgtawfaywgqgtlvtvsa
agggsggggsdiqmtqspaslsasvgetvtitcrasgnihnflawyqqkqgkspqvlvyn
aktladgvpsrfsgsgsgtqyslkinslqpedfgsyycqqfwstpytfgggtkleina