PDB entry 5lvq

View 5lvq on RCSB PDB site
Description: Crystal structure of human PCAF bromodomain in complex with compound-D (CPD-D), N-methyl-2-(tetrahydro-2H-pyran-4-yloxy)benzamide
Class: transferase
Keywords: signaling protein, bromodomain, histone acetyltransferase kat2b, histone, acetylation, acetyllysine, epigenetics, structural genomics consortium (sgc), transferase
Deposited on 2016-09-14, released 2016-10-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-01-11, with a file datestamp of 2017-01-06.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone acetyltransferase KAT2B
    Species: Homo sapiens [TaxId:9606]
    Gene: KAT2B, PCAF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5lvqa_
  • Chain 'B':
    Compound: Histone acetyltransferase KAT2B
    Species: Homo sapiens [TaxId:9606]
    Gene: KAT2B, PCAF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5lvqb_
  • Heterogens: EDO, 2LX, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5lvqA (A:)
smgkekskeprdpdqlystlksilqqvkshqsawpfmepvkrteapgyyevirfpmdlkt
mserlknryyvskklfmadlqrvftnckeynppeseyykcanilekfffskikeaglid

    Sequence, based on observed residues (ATOM records): (download) 
    >5lvqA (A:)
dpdqlystlksilqqvkshqsawpfmepvkrteapgyyevirfpmdlktmserlknryyv
skklfmadlqrvftnckeynppeseyykcanilekfffskikeaglid

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5lvqB (B:)
smgkekskeprdpdqlystlksilqqvkshqsawpfmepvkrteapgyyevirfpmdlkt
mserlknryyvskklfmadlqrvftnckeynppeseyykcanilekfffskikeaglid

    Sequence, based on observed residues (ATOM records): (download) 
    >5lvqB (B:)
rdpdqlystlksilqqvkshqsawpfmepvkrteapgyyevirfpmdlktmserlknryy
vskklfmadlqrvftnckeynppeseyykcanilekfffskikeagli