PDB entry 5lqf
View 5lqf on RCSB PDB site
Description: CDK1/CyclinB1/CKS2 in complex with NU6102
Class: transferase
Keywords: CDK1 CYCLIN B CKS2 CELL CYCLE NU6102, transferase
Deposited on
2016-08-17, released
2017-01-11
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-03-22, with a file datestamp of
2017-03-17.
Experiment type: XRAY
Resolution: 2.06 Å
R-factor: N/A
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cyclin-dependent kinase 1
Species: Homo sapiens [TaxId:9606]
Gene: CDK1, CDC2, CDC28A, CDKN1, P34CDC2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5lqfa1, d5lqfa2 - Chain 'B':
Compound: g2/mitotic-specific cyclin-b1
Species: Homo sapiens [TaxId:9606]
Gene: CCNB1, CCNB
Database cross-references and differences (RAF-indexed):
- Uniprot P14635
- conflict (6)
- conflict (77)
- conflict (189)
- Chain 'C':
Compound: Cyclin-dependent kinases regulatory subunit 2
Species: Homo sapiens [TaxId:9606]
Gene: CKS2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5lqfc_ - Chain 'D':
Compound: Cyclin-dependent kinase 1
Species: Homo sapiens [TaxId:9606]
Gene: CDK1, CDC2, CDC28A, CDKN1, P34CDC2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5lqfd1, d5lqfd2 - Chain 'E':
Compound: g2/mitotic-specific cyclin-b1
Species: Homo sapiens [TaxId:9606]
Gene: CCNB1, CCNB
Database cross-references and differences (RAF-indexed):
- Uniprot P14635
- conflict (6)
- conflict (77)
- conflict (189)
- Chain 'F':
Compound: Cyclin-dependent kinases regulatory subunit 2
Species: Homo sapiens [TaxId:9606]
Gene: CKS2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5lqff_ - Heterogens: 4SP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5lqfA (A:)
gplgsmedytkiekigegtygvvykgrhkttgqvvamkkirleseeegvpstaireisll
kelrhpnivslqdvlmqdsrlylifeflsmdlkkyldsippgqymdsslvksylyqilqg
ivfchsrrvlhrdlkpqnlliddkgtikladfglarafgipirvythevvtlwyrspevl
lgsarystpvdiwsigtifaelatkkplfhgdseidqlfrifralgtpnnevwpeveslq
dykntfpkwkpgslashvknldengldllskmliydpakrisgkmalnhpyfndldnqik
km
Sequence, based on observed residues (ATOM records): (download)
>5lqfA (A:)
lgsmedytkiekigegtygvvykgrhkttgqvvamkkirleseeegvpstaireisllke
lrhpnivslqdvlmqdsrlylifeflsmdlkkyldsippgqymdsslvksylyqilqgiv
fchsrrvlhrdlkpqnlliddkgtikladfglarafgipirvvtlwyrspevllgsarys
tpvdiwsigtifaelatkkplfhgdseidqlfrifralgtpnnevwpeveslqdykntfp
kwkpgslashvknldengldllskmliydpakrisgkmalnhpyfnd
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>5lqfC (C:)
gplgsmahkqiyysdkyfdehyeyrhvmlprelskqvpkthlmseeewrrlgvqqslgwv
hymihepephillfrrplpkdqqk
Sequence, based on observed residues (ATOM records): (download)
>5lqfC (C:)
mahkqiyysdkyfdehyeyrhvmlprelskqvpkthlmseeewrrlgvqqslgwvhymih
epephillfrrplp
- Chain 'D':
Sequence, based on SEQRES records: (download)
>5lqfD (D:)
gplgsmedytkiekigegtygvvykgrhkttgqvvamkkirleseeegvpstaireisll
kelrhpnivslqdvlmqdsrlylifeflsmdlkkyldsippgqymdsslvksylyqilqg
ivfchsrrvlhrdlkpqnlliddkgtikladfglarafgipirvythevvtlwyrspevl
lgsarystpvdiwsigtifaelatkkplfhgdseidqlfrifralgtpnnevwpeveslq
dykntfpkwkpgslashvknldengldllskmliydpakrisgkmalnhpyfndldnqik
km
Sequence, based on observed residues (ATOM records): (download)
>5lqfD (D:)
lgsmedytkiekigegtygvvykgrhkttgqvvamkkirleseeegvpstaireisllke
lrhpnivslqdvlmqdsrlylifeflsmdlkkyldsippgqymdsslvksylyqilqgiv
fchsrrvlhrdlkpqnlliddkgtikladfglarafgipirtlwyrspevllgsarystp
vdiwsigtifaelatkkplfhgdseidqlfrifralgtpnnevwpeveslqdykntfpkw
kpgslashvknldengldllskmliydpakrisgkmalnhpyfnd
- Chain 'E':
No sequence available.
- Chain 'F':
Sequence, based on SEQRES records: (download)
>5lqfF (F:)
gplgsmahkqiyysdkyfdehyeyrhvmlprelskqvpkthlmseeewrrlgvqqslgwv
hymihepephillfrrplpkdqqk
Sequence, based on observed residues (ATOM records): (download)
>5lqfF (F:)
mahkqiyysdkyfdehyeyrhvmlprelskqvpkthlmseeewrrlgvqqslgwvhymih
epephillfrrplp