PDB entry 5lj1
View 5lj1 on RCSB PDB site
Description: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 8-(((3R,4R,5S)-3-((4,4-difluorocyclohexyl)methoxy)-5-methoxypiperidin-4-yl)amino)-3-methyl-5-(5-methylpyridin-3-yl)-1,7-naphthyridin-2(1H)-one
Class: transcription
Keywords: INHIBITOR, HISTONE, EPIGENETIC READER, BROMODOMAIN, BRD4, BROMODOMAIN CONTAINING PROTEIN 4, ANTAGONIST, transcription
Deposited on
2016-07-17, released
2016-08-31
The last revision prior to the SCOPe 2.08 freeze date was dated
2016-09-14, with a file datestamp of
2016-09-09.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5lj1a_ - Heterogens: EDO, 6XX, HOH