PDB entry 5liy
View 5liy on RCSB PDB site
Description: Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor MK204
Class: oxidoreductase
Keywords: alpha-beta TIM barrel, cytosol, aldo-keto reductase, halogenated ligand, oxidoreductase
Deposited on
2016-07-15, released
2016-10-12
The last revision prior to the SCOPe 2.08 freeze date was dated
2016-11-02, with a file datestamp of
2016-10-28.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'X':
Compound: Aldo-keto reductase family 1 member B10
Species: Homo sapiens [TaxId:9606]
Gene: AKR1B10, AKR1B11
Database cross-references and differences (RAF-indexed):
- Uniprot O60218 (0-315)
- engineered mutation (124)
- engineered mutation (300)
Domains in SCOPe 2.08: d5liyx_ - Heterogens: NAP, DQP, EDO, HOH