PDB entry 5lab

View 5lab on RCSB PDB site
Description: Crystal structure of the catalytic domain of human MMP12 complexed with the inhibitor NNGH
Class: hydrolase
Keywords: hydrolase mmp-12, hydrolase
Deposited on 2016-06-14, released 2016-08-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-08-10, with a file datestamp of 2016-08-05.
Experiment type: XRAY
Resolution: 1.34 Å
R-factor: N/A
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Macrophage metalloelastase
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP12, HME
    Database cross-references and differences (RAF-indexed):
    • Uniprot P39900 (1-158)
      • initiating methionine (0)
      • engineered mutation (66)
    Domains in SCOPe 2.07: d5laba1, d5laba2
  • Heterogens: ZN, CA, NGH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5labA (A:)