PDB entry 5kyf

View 5kyf on RCSB PDB site
Description: Crystal structure of USP7 catalytic domain [L299A] mutant in complex with ubiquitin
Class: hydrolase
Keywords: USP7 catalytic domain, deubiquitinase, L299A mutant, ubiquitin, HYDROLASE
Deposited on 2016-07-21, released 2017-08-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-08-09, with a file datestamp of 2017-08-04.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: Ubiquitin carboxyl-terminal hydrolase 7
    Species: Homo sapiens [TaxId:9606]
    Gene: USP7, HAUSP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q93009 (4-End)
      • engineered mutation (95)
    Domains in SCOPe 2.06: d5kyfb_
  • Chain 'C':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5kyfc_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5kyfB (B:)
    gshmkkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrv
    fyelqhsdkpvgtkkltksfgwetldsfmqhdvqeacrvlldnvenkmkgtcvegtipkl
    frgkmvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydage
    hglqeaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpk
    dpanyilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdd
    dlsvrhctnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaqk
    

    Sequence, based on observed residues (ATOM records): (download)
    >5kyfB (B:)
    kkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyel
    qhsdkpvgtkkltksfgwetldsfmqhdvqeacrvlldnvenkmkgtcvegtipklfrgk
    mvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglq
    eaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdpan
    yilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdvrhct
    naymlvyiresklsevlqavtdhdipqqlverlqeekrie
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5kyfC (C:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg