PDB entry 5kyc
View 5kyc on RCSB PDB site
Description: Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin (malonate bound)
Class: hydrolase
Keywords: USP7 catalytic domain, deubiquitinase, V302K mutation, HYDROLASE
Deposited on
2016-07-21, released
2017-08-09
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-02-20, with a file datestamp of
2019-02-15.
Experiment type: XRAY
Resolution: 1.43 Å
R-factor: N/A
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'B':
Compound: Ubiquitin carboxyl-terminal hydrolase 7
Species: Homo sapiens [TaxId:9606]
Gene: USP7, HAUSP
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5kycb_ - Chain 'C':
Compound: Polyubiquitin-B
Species: Homo sapiens [TaxId:9606]
Gene: UBB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5kycc_ - Heterogens: MLA, GOL, HOH
PDB Chain Sequences:
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5kycB (B:)
gshmkkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrv
fyelqhsdkpvgtkkltksfgwetldsfmqhdvqelcrklldnvenkmkgtcvegtipkl
frgkmvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydage
hglqeaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpk
dpanyilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdd
dlsvrhctnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaqk
Sequence, based on observed residues (ATOM records): (download)
>5kycB (B:)
htgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyelqh
sdkpvgtkkltksfgwetldsfmqhdvqelcrklldnvenkmkgtcvegtipklfrgkmv
syiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglqea
ekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdpanyi
lhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdddlsvrh
ctnaymlvyiresklsevlqavtdhdipqqlverlqeekr
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>5kycC (C:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg