PDB entry 5kwy
View 5kwy on RCSB PDB site
Description: Structure of human NPC1 middle lumenal domain bound to NPC2
Class: transport protein
Keywords: human protein complex, NPC1, NPC2, TRANSPORT PROTEIN
Deposited on
2016-07-19, released
2016-08-24
The last revision prior to the SCOPe 2.06 freeze date was dated
2016-08-24, with a file datestamp of
2016-08-18.
Experiment type: XRAY
Resolution: 2.41 Å
R-factor: N/A
AEROSPACI score: 0.22
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Niemann-Pick C1 protein
Species: Homo sapiens [TaxId:9606]
Gene: NPC1
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: Niemann-Pick C1 protein
Species: Homo sapiens [TaxId:9606]
Gene: NPC1
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: Epididymal secretory protein E1
Species: Homo sapiens [TaxId:9606]
Gene: NPC2, HE1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d5kwyc1, d5kwyc2 - Chain 'D':
Compound: Epididymal secretory protein E1
Species: Homo sapiens [TaxId:9606]
Gene: NPC2, HE1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d5kwyd_ - Heterogens: NAG, C3S, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>5kwyC (C:)
epvqfkdcgsvdgvikevnvspcptqpcqlskgqsysvnvtftsniqsksskavvhgilm
gvpvpfpipepdgcksgincpiqkdktysylnklpvkseypsiklvvewqlqddknqslf
cweipvqivshla
- Chain 'D':
Sequence, based on SEQRES records: (download)
>5kwyD (D:)
epvqfkdcgsvdgvikevnvspcptqpcqlskgqsysvnvtftsniqsksskavvhgilm
gvpvpfpipepdgcksgincpiqkdktysylnklpvkseypsiklvvewqlqddknqslf
cweipvqivshla
Sequence, based on observed residues (ATOM records): (download)
>5kwyD (D:)
epvqfkdcgsvdgvikevnvspcptqpcqlskgqsysvnvtftsniqsksskavvhgilm
gvpvpfpipepdgcksgincpiqkdktysylnklpvkseypsiklvvewqlqddknqslf
cweipvqivshl