PDB entry 5kvd

View 5kvd on RCSB PDB site
Description: Zika specific antibody, ZV-2, bound to ZIKA envelope DIII
Class: viral protein/immune system
Keywords: ZIKA VIRUS, ENVELOPE DIII, VIRAL PROTEIN, antibody, IgG2c, structural genomics, Center for Structural Genomics of Infectious Diseases, CSGID., VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2016-07-14, released 2016-08-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-08-24, with a file datestamp of 2016-08-18.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: ZIKA Envelope DIII
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A024B7W1 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.07: d5kvde_
  • Chain 'H':
    Compound: ZV-2 Antibody Fab Heavy Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 5KVD (0-221)
  • Chain 'L':
    Compound: ZV-2 Antibody Fab Light Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 5KVD (0-219)
    Domains in SCOPe 2.07: d5kvdl1, d5kvdl2
  • Heterogens: NA, MES, EDO, HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >5kvdE (E:)
    mrlkgvsyslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgr
    litanpvitestenskmmleldppfgdsyivigvgekkithhwhrsgsti
    

    Sequence, based on observed residues (ATOM records): (download)
    >5kvdE (E:)
    mrlkgvsyslctaaftftkipaetlhgtvtvevqyagtdgpckvpaqmavdmqtltpvgr
    litanpvitestenskmmleldppfgdsyivigvgekkithhwhrsgs
    

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5kvdL (L:)
    divmtqspsslsvsagekvtlsckssqsllhsgnqknylawyqqkpgqapklliygastr
    esgvpdrftgsgsgtdftltissvqaedlavyycqndhsypltfgagtklelkradaapt
    vsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstys
    msstltltkdeyerhnsytceathktstspivksfnrnec