PDB entry 5kmw

View 5kmw on RCSB PDB site
Description: TOHO1 Beta lactamase mutant E166A/R274N/R276N -benzyl penicillin complex
Class: hydrolase
Keywords: Class A beta-lactamase, substrate recognition, acyl-enzyme, HYDROLASE
Deposited on 2016-06-27, released 2017-03-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-03-01, with a file datestamp of 2017-02-24.
Experiment type: XRAY
Resolution: 1.1 Å
R-factor: N/A
AEROSPACI score: 0.73 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-lactamase toho-1
    Species: Escherichia coli [TaxId:562]
    Gene: bla
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q47066 (0-255)
      • engineered mutation (136)
      • engineered mutation (242)
      • engineered mutation (244)
    Domains in SCOPe 2.06: d5kmwa_
  • Heterogens: SO4, PNM, PNN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5kmwA (A:)
vqqqlealekssggrlgvalintadnsqilyraderfamcstskvmaaaavlkqsesdkh
llnqrveikksdlvnynpiaekhvngtmtlaelgaaalqysdntamnkliahlggpdkvt
afarslgdetfrldrtaptlntaipgdprdtttplamaqtlknltlgkalaetqraqlvt
wlkgnttgsasiraglpkswvvgdktgsgdygttndiaviwpenhaplvlvtyftqpeqk
aenrndilaaaakivt