PDB entry 5kde

View 5kde on RCSB PDB site
Description: Inorganic pyrophosphatase from Mycobacterium tuberculosis in complex with inhibitor 1 and inorganic pyrophosphate
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase, pyrophosphatase, drug target, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2016-06-08, released 2016-09-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-12-21, with a file datestamp of 2016-12-16.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inorganic pyrophosphatase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: ppa, Rv3628, MTCY15C10.24
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WI55 (9-End)
      • expression tag (8)
    Domains in SCOPe 2.08: d5kdea1, d5kdea2
  • Heterogens: 6RT, POP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5kdeA (A:)
mahhhhhhamqfdvtieipkgqrnkyevdhetgrvrldrylytpmayptdygfiedtlgd
dgdpldalvllpqpvfpgvlvaarpvgmfrmvdehggddkvlcvpagdprwdhvqdigdv
pafeldaikhffvhykdlepgkfvkaadwvdraeaeaevqrsverfkagth

    Sequence, based on observed residues (ATOM records): (download) 
    >5kdeA (A:)
amqfdvtieipkgqrnkyevdhetgrvrldrylytpmayptdygfiedtlgddgdpldal
vllpqpvfpgvlvaarpvgmfrmvdehggddkvlcvpagdprwdhvqdigdvpafeldai
khffvhykdlepgkfvkaadwvdraeaeaevqrsverfkag