PDB entry 5kcj

View 5kcj on RCSB PDB site
Description: Structure of the human GluN1/GluN2A LBD in complex with GNE6901
Class: transport protein
Keywords: GRIN1, GRIN2A, NMDA receptor, glycine, glutamate, TRANSPORT PROTEIN
Deposited on 2016-06-06, released 2016-07-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-07-13, with a file datestamp of 2016-07-08.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor ionotropic, NMDA 2A
    Species: Homo sapiens [TaxId:9606]
    Gene: GRIN2A, NMDAR2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12879 (Start-140)
      • linker (141-142)
    • Uniprot Q12879 (143-End)
    Domains in SCOPe 2.08: d5kcja_
  • Chain 'B':
    Compound: Glutamate receptor ionotropic, NMDA 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Grin1, Nmdar1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q05586 (Start-152)
      • linker (153-154)
    • Uniprot Q05586 (155-End)
    Domains in SCOPe 2.08: d5kcjb_
  • Heterogens: ACT, GLU, GLY, 6RM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5kcjA (A:)
gspddnhlsivtleeapfvivedidpltetcvrntvpcrkfvkinnstnegmnvkkcckg
fcidilkklsrtvkftydlylvtngkhgkkvnnvwngmigevvyqravmavgsltineer
sevvdfsvpfvetgisvmvsrgtqvtglsdkkfqrphdysppfrfgtvpngsternirnn
ypymhqymtkfnqkgvedalvslktgkldafiydaavlnykagrdegcklvtigsgyifa
ttgygialqkgspwkrqidlallqfvgdgemeeletlwltgichn

    Sequence, based on observed residues (ATOM records): (download) 
    >5kcjA (A:)
dnhlsivtleeapfvivedidpltetcvrntvpcrkfvkinnstnegmnvkkcckgfcid
ilkklsrtvkftydlylvtngkhgkkvnnvwngmigevvyqravmavgsltineersevv
dfsvpfvetgisvmvsrgtqvtglsdkkfqrphdysppfrfgtvpngsternirnnypym
hqymtkfnqkgvedalvslktgkldafiydaavlnykagrdegcklvtigsgyifattgy
gialqkgspwkrqidlallqfvgdgemeeletlwltgic

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5kcjB (B:)
gsmstrlkivtihqepfvyvkptlsdgtckeeftvngdpvkkvictgpndtspgsprhtv
pqccygfcidlliklartmnftyevhlvadgkfgtqervnnsnkkewngmmgellsgqad
mivapltinneraqyiefskpfkyqgltilvkkgtritgindprlrnpsdkfiyatvkqs
svdiyfrrqvelstmyrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlv
ttgelffrsgfgigmrkdspwkqnvslsilkshengfmedldktwvryqecds

    Sequence, based on observed residues (ATOM records): (download) 
    >5kcjB (B:)
trlkivtihqepfvyvkptlsdgtckeeftvngdpvkkvictgpndtspgsprhtvpqcc
ygfcidlliklartmnftyevhlvadgkfgtqervnkkewngmmgellsgqadmivaplt
inneraqyiefskpfkyqgltilvkkgtritgindprlrnpsdkfiyatvkqssvdiyfr
rqvelstmyrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlvttgelff
rsgfgigmrkdspwkqnvslsilkshengfmedldktwvr