PDB entry 5k9r
View 5k9r on RCSB PDB site
Description: PDE10a with imidazopyrazine inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2016-06-01, released
2016-08-24
The last revision prior to the SCOPe 2.08 freeze date was dated
2016-08-24, with a file datestamp of
2016-08-18.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Species: Homo sapiens [TaxId:9606]
Gene: PDE10A
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5k9ra_ - Chain 'B':
Compound: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Species: Homo sapiens [TaxId:9606]
Gene: PDE10A
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5k9rb_ - Heterogens: ZN, MG, 6RC, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>5k9rA (A:)
glmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfeleklcrfimsvkk
nyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhrgfsnsylqk
fdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlal
yfgnrkqleemyqtgslnlnnqshrdrvislmmtacdlcsvtklwpvtkltandiyaefw
aegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrd
nlsqwekvirge
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>5k9rB (B:)
glmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfeleklcrfimsvkk
nyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhrgfsnsylqk
fdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlal
yfgnrkqleemyqtgslnlnnqshrdrvislmmtacdlcsvtklwpvtkltandiyaefw
aegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrd
nlsqwekvirge