PDB entry 5k01

View 5k01 on RCSB PDB site
Description: Crystal Structure of COMT in complex with 2,7-dimethyl-3-(1H-pyrazol-3-yl)imidazo[1,2-a]pyridine
Class: transferase
Keywords: METHYLTRANSFERASE, NEUROTRANSMITTER DEGRADATION, CATECHOL, transferase
Deposited on 2016-05-17, released 2016-09-07
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-09-07, with a file datestamp of 2016-09-02.
Experiment type: XRAY
Resolution: 1.38 Å
R-factor: N/A
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Catechol O-methyltransferase
  Species: Rattus norvegicus [TaxId:10116]
  Gene: COMT
  Database cross-references and differences (RAF-indexed):
  • Uniprot P22734 (0-213)
    • conflict (8-9)
    • conflict (11)
    • conflict (13)
    • conflict (15)
    • conflict (18-19)
    • conflict (31)
    • conflict (42)
    • conflict (45)
    • conflict (47)
    • conflict (52)
    • conflict (54-55)
    • conflict (58-59)
    • conflict (78)
    • conflict (84)
    • conflict (86)
    • conflict (98)
    • conflict (100-101)
    • conflict (105-106)
    • conflict (111-113)
    • conflict (119)
    • conflict (153)
    • conflict (170)
    • conflict (173)
    • conflict (179)
    • conflict (185)
    • conflict (192)
    • conflict (194)
    • conflict (198-199)
    • conflict (210)
    • conflict (213)
  Domains in SCOPe 2.06: d5k01a_
• Heterogens: 6OW, K, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5k01A (A:)
  dtkeqrilryvqqnakpgdpqsvleaidtyctqkewamnvgdakgqimdavireyspslv
  lelgaycgysavrmarllqpgarlltmeinpdcaaitqqmlnfaglqdkvtilngasqdl
  ipqlkkkydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpdflay
  vrgsssfecthyssyleymkvvdglekaiyqgps