PDB entry 5iyy

View 5iyy on RCSB PDB site
Description: X-ray structure of neuropilin-1 b1 domain complexed with Arg-4 ligand.
Class: signaling protein
Keywords: SIGNALING PROTEIN, Neuropilin-1, Angiogenesis
Deposited on 2016-03-24, released 2017-04-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-04-05, with a file datestamp of 2017-03-31.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuropilin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: NRP1, NRP, VEGF165R
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14786 (3-157)
      • expression tag (2)
    Domains in SCOPe 2.07: d5iyya1, d5iyya2
  • Chain 'B':
    Compound: Neuropilin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: NRP1, NRP, VEGF165R
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14786 (3-157)
      • expression tag (1-2)
    Domains in SCOPe 2.07: d5iyyb1, d5iyyb2
  • Heterogens: R40, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5iyyA (A:)
    ghmfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvd
    lgllrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptd
    vvvavfpkplitrfvrikpatwetgismrfevygckit
    

    Sequence, based on observed residues (ATOM records): (download)
    >5iyyA (A:)
    mfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvdlg
    llrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptdvv
    vavfpkplitrfvrikpatwetgismrfevygckit
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5iyyB (B:)
    ghmfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvd
    lgllrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptd
    vvvavfpkplitrfvrikpatwetgismrfevygckit
    

    Sequence, based on observed residues (ATOM records): (download)
    >5iyyB (B:)
    hmfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvdl
    gllrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptdv
    vvavfpkplitrfvrikpatwetgismrfevygckit